Evidence map›Paper›PMID 41349532›Full record

ArticleCurrent biology : CB2025

Neurons in auditory cortex integrate information within a constrained and context-invariant temporal window.

Magdalena Sabat, Hortense Gouyette, Quentin Gaucher, Mateo López Espejo, Stephen V David, Sam Norman-Haignere, Yves Boubenec

Abstract read
In one paragraph

Article in Current biology : CB, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Magdalena SabatLaboratoire de Neurosciences Cognitives et Computationnelles, Département d'études cognitives, INSERM, PSL University, 29 rue d'Ulm, 75005 Paris, France; Laboratoire des systèmes perceptifs, Département d'études cognitives, PSL University, 29 rue d'Ulm, 75005 Paris, France. Electronic address: magdalena.sabat@ens.psl.eu.
Hortense GouyetteLaboratoire des systèmes perceptifs, Département d'études cognitives, PSL University, 29 rue d'Ulm, 75005 Paris, France.
Quentin GaucherSorbonne Université, CNRS, Inserm, Institut de la Vision, 17 Rue Moreau, Paris 75012, France.
Mateo López EspejoOregon Hearing Research Center, Department of Otolaryngology-Head & Neck Surgery, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239-3098, USA.
Stephen V DavidOregon Hearing Research Center, Department of Otolaryngology-Head & Neck Surgery, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239-3098, USA.
Sam Norman-HaignereDepartment of Biostatistics & Computational Biology, Department of Neuroscience, University of Rochester Medical Center, 265 Crittenden Boulevard, Rochester, NY 14642, USA; Department of Brain & Cognitive Sciences, Department of Biomedical Engineering, University of Rochester, Meliora Hall, Rochester, NY 14627, USA. Electronic address: samuel_norman-haignere@urmc.rochester.edu.
Yves BoubenecLaboratoire des systèmes perceptifs, Département d'études cognitives, PSL University, 29 rue d'Ulm, 75005 Paris, France. Electronic address: yves.boubenec@ens.fr.

Funding

Top-down control of auditory processing in the cortico-collicular network (Administrative Supplement)R01DC014950 · NIDCD · OREGON HEALTH & SCIENCE UNIVERSITY · PI DAVID, STEPHEN V · 2016 to 2025
$3.5M
Revealing the organization and functional significance of neural timescales inauditory cortexR00DC018051 · NIDCD · UNIVERSITY OF ROCHESTER · PI NORMAN-HAIGNERE, SAMUEL V · 2022 to 2024
$732k
NIDCD NIH HHS R00 DC018051NIDCD NIH HHS R01 DC014950
6 · The paper itself

Abstract

Much remains unknown about the computations that allow animals to flexibly integrate across multiple timescales in natural sounds. One key question is whether multiscale integration is accomplished by diverse populations of neurons, each of which integrates information within a constrained temporal window, or whether individual units effectively integrate across many different temporal scales depending on the information rate. Here, we show that responses from neurons throughout the ferret auditory cortex are nearly completely unaffected by sounds falling beyond a time-limited "integration window." This window varies substantially across cells within the auditory cortex (∼15 to ∼150 ms), increasing substantially from the primary to non-primary auditory cortex across all cortical layers, but is unaffected by the information rate of sound. These results indicate that multiscale computation is predominantly accomplished by diverse and hierarchically organized neural populations, each of which integrates information within a highly constrained temporal window.

Indexed as

Auditory CortexAuditory PerceptionFerretsNeuronsAcoustic StimulationAnimalsFemaleMaleTime Factorsauditory cortexauditory neuroscienceinformation rateintegration windowsintracranial neurophysiologymultiscale computationsingle-cell responsestemporal integrationtemporal invariancetime-yoked integration

Identifiers

PMID41349532
PMCPMC13331568

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.