Evidence map›Paper›PMID 41350212›Full record

ReviewTrends in cognitive sciences2026

Orbitofrontal-sensory cortical interactions in learning and adaptive decision-making.

Rohan Rao, Hugo Six, Aurelio Cortese, Abhishek Banerjee

Abstract readReview
In one paragraph

Review in Trends in cognitive sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rohan RaoBiosciences Institute, Newcastle University, Newcastle, UK; Blizard Institute, Queen Mary University of London, London, UK; Adaptive Decisions Laboratory, Department of Pharmacology, University of Oxford, Oxford, UK.
Hugo SixDepartment of Decoded Neurofeedback, ATR Computational Neuroscience Laboratories, Kyoto, Japan.
Aurelio CorteseDepartment of Decoded Neurofeedback, ATR Computational Neuroscience Laboratories, Kyoto, Japan; Department of Biomedical Engineering, Sungkyunkwan University, Suwon, South Korea; Center for Neuroscience Imaging Research, Institute for Basic Science, Suwon, South Korea. Electronic address: cortese.aurelio@gmail.com.
Abhishek BanerjeeBlizard Institute, Queen Mary University of London, London, UK; Adaptive Decisions Laboratory, Department of Pharmacology, University of Oxford, Oxford, UK. Electronic address: abhishek.banerjee@pharm.ox.ac.uk.

Funding

Wellcome Trust 227782
6 · The paper itself

Abstract

The orbitofrontal cortex (OFC) is a hub for value-guided decision-making, linked reciprocally with both cortical and subcortical regions. While projections from sensory areas to the OFC - and vice versa - are known to support goal-directed learning, these projections have often been studied in isolation, and their joint effect remains poorly understood. Here, we revisit these circuits through a unifying computational framework. We propose that sensory cortices send compressed task knowledge to the OFC to build abstract task models, while OFC feedback provides teaching signals that reshape sensory representations within the cortical hierarchy. This bidirectional exchange equips sensory areas with cognitive functions that extend well beyond passive feature detection, with significant implications for our understanding of learning, cognitive models, and artificial neural networks.

Indexed as

Decision MakingLearningPrefrontal CortexAnimalsHumansModels, NeurologicalNeural Pathwaysattentioncognitive mapsorbitofrontal cortexreinforcement learningsensory cortexvalue-guided decision-making

Identifiers

PMID41350212
PMCPMC7618814

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.