Evidence map›Paper›PMID 41350330›Full record

ArticleScientific reports2025

Impact of structurally transphobic policy environment on harmful alcohol and substance use among transgender and nonbinary adults.

Abby Baker, Teresa DeAtley, Adedotun Ogunbajo, Ruby Lucas, Emerson Dusic, Jessie M Garcia Gutiérrez, Audren J K Bambilla, Nathaniel M Widmann, Daphne Suen, Aleks Martin and 9 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Abby BakerDepartment of Family and Preventive Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA. abby.baker2001@gmail.com.
Teresa DeAtleyDepartment of Family and Preventive Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.
Adedotun OgunbajoRAND Corporation, Los Angeles, CA, USA.
Ruby LucasDepartments of Epidemiology and Health Systems and Population Health, University of Washington School of Public Health, Seattle, WA, USA.
Emerson DusicDepartments of Epidemiology and Health Systems and Population Health, University of Washington School of Public Health, Seattle, WA, USA.
Jessie M Garcia GutiérrezDepartments of Epidemiology and Health Systems and Population Health, University of Washington School of Public Health, Seattle, WA, USA.
Audren J K BambillaDepartments of Epidemiology and Health Systems and Population Health, University of Washington School of Public Health, Seattle, WA, USA.
Nathaniel M WidmannDepartments of Epidemiology and Health Systems and Population Health, University of Washington School of Public Health, Seattle, WA, USA.
Daphne SuenDepartments of Epidemiology and Health Systems and Population Health, University of Washington School of Public Health, Seattle, WA, USA.
Aleks MartinPublic Health - Seattle & King County, WA, Washington, USA.
Alic ShookCollege of Nursing, Seattle University, Seattle, WA, USA.
Deborah SchwarzDepartments of Epidemiology and Health Systems and Population Health, University of Washington School of Public Health, Seattle, WA, USA.
Genya ShimkinDepartments of Epidemiology and Health Systems and Population Health, University of Washington School of Public Health, Seattle, WA, USA.
Vanessa GrandberryWashington Department of Health, Olympia, WA, USA.
Xero XanaduDepartments of Epidemiology and Health Systems and Population Health, University of Washington School of Public Health, Seattle, WA, USA.
Don OperarioDepartment of Behavioral, Social, and Health Education Sciences, Emory University Rollins School of Public Health, Atlanta, GA, USA.
Trace KershawDepartment of Social and Behavioral Sciences, Yale University School of Public Health, New Haven, CT, USA.
Kristi E GamarelDepartment of Health Behavior and Health Education, University of Michigan School of Public Health, Ann Arbor, MI, USA.
Arjee RestarDepartment of Social and Behavioral Sciences, Yale University School of Public Health, New Haven, CT, USA. arjee.restar@yale.edu.

Funding

Research Education Institute for Dynamic Scholars (REIDS)R25MH087217 · NIMH · YALE UNIVERSITY · PI Jasmine Abrams, Trace S Kershaw · 2010 to 2026
$3.9M
Developing and testing a telehealth intervention to increase HIV pre-exposure prophylaxis uptake and adherence among sexual minority men in NigeriaK01MH129165 · NIMH · RAND CORPORATION · PI Adedotun Ogunbajo · 2022 to 2026
$980k
NIH HHS K01MH129165NIH HHS R25MH087217
6 · The paper itself

Abstract

Previous studies have demonstrated high prevalence of alcohol and substance use behaviors among transgender and gender-diverse (TGD) communities. Considering the recency of anti-trans policies in the US, it is critical to understand whether structural anti-trans factors are associated with substance use outcomes. To fill this gap, we examined the associations between factors that make up a structurally anti-trans policy environment and unhealthy alcohol use and drug use among TGD adults. Using data from the Priority Assessment in Trans Health (PATH) Project (n = 797), multivariable regression modeling using nonparametric bootstrapping methods (resampling = 1000) were used to assess associations between structurally anti-trans policy environment indicators and harmful alcohol use (HAU) and harmful drug use (HDU) (abuse, dependence, disorders, etc.). The sample was predominately comprised of young adult trans women (81.9%), ages 25-34 (81.7%). Over one-third identified as people of color (39.7%). Overall, 52.8% reported HAU and 5.6% reported HDU. Accurate knowledge of state-level anti-hate-crime laws was associated with reduced odds of HAU (OR = 0.69 [95% CI: 0.53, 0.90]; p = 0.006). In a separate model, higher awareness of anti-trans bills was associated with increased odds of reporting HDU (OR = 1.62 [95% CI: 1.09, 2.40]; p = 0.02). There were no significant differences between concerns about trans rights being taken away and alcohol or drug use. Findings indicate that awareness of anti-trans bills is associated with increased unhealthy drug use, while knowledge of state-level anti-hate-crime laws is associated with decreased unhealthy alcohol use. Protecting social safety should be prioritized for TGD individuals, as this may serve as a protective factor against risk behaviors.

Indexed as

AlcoholismSubstance-Related DisordersTransgender PersonsAdultAlcohol DrinkingFemaleHumansMaleMiddle AgedUnited StatesYoung Adult

Identifiers

PMID41350330
PMCPMC12680625

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.