ArticleBMC geriatrics2025
Depressive symptoms affect frailty through attitudes to aging: a cross-lagged analysis.
Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Analysis of potential categories of depression in older adults with chronic illness.Frontiers in psychology · 2026Article
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Authors and funding
3 authors.
Funding
Abstract
objectiveThe bidirectional causality between frailty and depressive symptoms (DS) in older adults were investigated, while the potential psychological mechanism remains unclear. This study aimed to explore the mediation role of attitudes to aging (AA) in their reciprocal relationships.
methodsData was collected from a community-based prospective cohort in Shanghai, which included 4,082 participants aged 60 and above. Frailty, DS, and AA were assessed using the Chinese Frailty Screening Scale-10, the Patient Health Questionnaire-9, and the Attitudes to Aging Questionnaire-12, respectively. A cross-lagged model was employed to investigate the reciprocal relationship between frailty and DS, as well as to estimate the mediating effect of AA.
resultsThe findings revealed significant correlations between frailty, DS, and AA at both measurement points. In the cross-lagged model, after controlling for covariates, we observed a bidirectional causality between frailty and DS. Specifically, greater frailty was associated with higher levels of DS (β = 0.142, P < 0.001), and higher levels of DS similarly predicted increased frailty (β = 0.058, P = 0.006). When AA were included in the cross-lagged model, results showed that older adults with more positive AA significantly predicted lower future levels of DS (β=-0.051, P < 0.001) and frailty (β=-0.055, P < 0.001). Mediation analyses indicated that AA had a significant mediating effect (β = 0.003, P = 0.029) between DS and frailty, although this effect was not reciprocated (P = 0.242).
conclusionThese findings underscored the importance of promoting positive AA as preventive measures against both frailty and DS. They also provided valuable insights into the mechanisms underlying the relationship between depression and frailty in older adults.
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