Evidence map›Paper›PMID 41350877›Full record

ArticleHarm reduction journal2025

Microbiological contamination in androgens from the black market.

T J Verdegaal, P Bond, M J H M Jansen, M Peijs, M Huyers, J J J M Stohr, W de Ronde, D L Smit

Abstract read
In one paragraph

Article in Harm reduction journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

T J VerdegaalDepartment of Internal Medicine, Spaarne Gasthuis, Boerhaavelaan 22, 2035 RC, Haarlem, North Holland, Netherlands. tverdegaal@spaarnegasthuis.nl.
P BondDepartment of Performance and Image-Enhancing Drugs Research, Android Health Clinic, Leidse Rijn 31, De Meern, 3454 PZ, Utrecht, Netherlands.
M J H M JansenDepartment of Performance and Image-Enhancing Drugs Research, Android Health Clinic, Leidse Rijn 31, De Meern, 3454 PZ, Utrecht, Netherlands.
M PeijsDepartment of Medical Microbiology and Immunology, Elisabeth- TweeSteden Hospital, Doctor Deelenlaan 5, 5042 AD, Tilburg, North Brabant, Netherlands.
M HuyersDepartment of Medical Microbiology and Immunology, Elisabeth- TweeSteden Hospital, Doctor Deelenlaan 5, 5042 AD, Tilburg, North Brabant, Netherlands.
J J J M StohrDepartment of Medical Microbiology and Immunology, Elisabeth- TweeSteden Hospital, Doctor Deelenlaan 5, 5042 AD, Tilburg, North Brabant, Netherlands.
W de RondeDepartment of Internal Medicine, Spaarne Gasthuis, Boerhaavelaan 22, 2035 RC, Haarlem, North Holland, Netherlands.
D L SmitDepartment of Performance and Image-Enhancing Drugs Research, Android Health Clinic, Leidse Rijn 31, De Meern, 3454 PZ, Utrecht, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAndrogens from the black market are often produced in clandestine laboratories without adherence to hygienic manufacturing processes. Consequently, users may face an increased risk of developing injection-related infections caused by microbiological contamination. This study aimed to determine the presence of microbiological contamination in androgens from the black market.

methodsCharacteristics of submitted androgen product were registered. Androgen products were submitted to aerobic and anaerobic bacterial culture using direct inoculation of agar plates and enrichment using BD BACTEC™ Peds Plus Medium blood culture bottles. Participants who submitted products were monitored for injection-related infections.

resultsBacterial contamination was detected in two of 22 used multidose vials (9%) and one of 41 unused ampules and multidose vials (2%). Identified species included Bacillus spp., Staphylococcus epidermidis, Staphylococcus warneri, Staphylococcus saprophyticus and Micrococcus luteus. None of the participants developed injection-related infections linked to contaminated products.

conclusionBoth used and unused androgens from the black market can contain bacteria. This can put users at risk for serious injection-related health problems such as abscesses. This study underlines the importance of warning androgen users about these underrecognized injection-related risks.

trial registrationStudy number: NL77191.028.21. Registration date: 2 June 2021.

Indexed as

AndrogensDrug ContaminationAdultBacteriaHumansMaleAndrogensAnabolic steroidsAndrogen abuseMicrobiological contaminationPerformance and image-enhancing drugs

Identifiers

PMID41350877
PMCPMC12797776

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.