Evidence map›Paper›PMID 41353444›Full record

ArticleNature communications2025

Occupational physical activity and incidence and mortality of 14 cancers in 404,249 adults.

Cristina Cadenas-Sanchez, Miguel Adriano Sanchez-Lastra, Jakob Tarp, Ulf Ekelund, Knut Eirik Dalene

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cristina Cadenas-SanchezDepartment of Physical Education and Sports, Faculty of Sports Science, Sport and Health University Research Institute (iMUDS), University of Granada; CIBEROBN, ISCIII, Granada, Spain. cadenas@ugr.es.ORCID http://orcid.org/0000-0002-4513-9108
Miguel Adriano Sanchez-LastraOslo Research Centre for Physical Activity and Population Health (ORC-PAPH), Department of Sports Medicine, Norwegian School of Sports Sciences, Oslo, Norway.
Jakob TarpOslo Research Centre for Physical Activity and Population Health (ORC-PAPH), Department of Sports Medicine, Norwegian School of Sports Sciences, Oslo, Norway.
Ulf EkelundOslo Research Centre for Physical Activity and Population Health (ORC-PAPH), Department of Sports Medicine, Norwegian School of Sports Sciences, Oslo, Norway.
Knut Eirik DaleneDepartment of Chronic Diseases, Norwegian Institute of Public Health, Oslo, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leisure physical activity is considered protective against several cancers, but the impact of physical activity at work remains unclear. We analyze data from over 400,000 Norwegian adults followed for a median of 27 years to examine how different levels of occupational physical activity are associated with cancer incidence and mortality. Participants report their typical work activity as sedentary, walking, walking-and-lifting, or heavy labor. Here we show that individuals with more physically active jobs have a lower risk of developing several cancers (i.e., endometrial, colon, breast, rectal, and prostate), and to a lesser extent, the risk of breast cancer mortality. However, occupational physical activity is also associated with increased risk of esophageal and kidney cancer death. These findings suggest that occupational physical activity may lower the incidence of some cancers but are associated with a higher mortality from other cancer types. Understanding these patterns could help tailor public health recommendations related to physical activity and occupational health.

Indexed as

ExerciseNeoplasmsAdultAgedFemaleHumansIncidenceMaleMiddle AgedNorwayOccupational HealthOccupationsRisk Factors

Identifiers

PMID41353444
PMCPMC12698860

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.