Evidence map›Paper›PMID 41353764›Full record

ReviewMagnetic resonance in medicine2026

Technical Review of Magnetic Resonance Fingerprinting Applications in Cerebral Physiology.

Chieh-Te Lin, Hanzhang Lu, Audrey P Fan

Abstract readReview
In one paragraph

Review in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chieh-Te LinDepartment of Biomedical Engineering, University of California, Davis, Davis, California, USA.ORCID https://orcid.org/0000-0001-5262-1050
Hanzhang LuDepartment of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Audrey P FanDepartment of Biomedical Engineering, University of California, Davis, Davis, California, USA.

Funding

TRD 4: Platforms for multi-modal and multi-scale imaging dataP41EB031771 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Hanzhang Lu, Peter CM Van Zijl · 2021 to 2026
$9.9M
MR fingerprinting (MRF) perfusion imaging in cerebral vascular diseaseR01NS106711 · NINDS · JOHNS HOPKINS UNIVERSITY · PI LU, HANZHANG · 2018 to 2022
$2.2M
NIH HHS P41 EB031771NIH HHS R01 NS106711NIH HHS R21-EB032485
6 · The paper itself

Abstract

Magnetic resonance fingerprinting (MRF) enables quantitative MRI by allowing the simultaneous mapping of multiple tissue properties through innovative acquisition and computational methods. This review focuses on the application of MRF techniques to cerebral physiology, emphasizing advancements in vascular imaging and the integration of biophysical modeling. We discuss the principles of MRF, its adaptation to quantify hemodynamic and vascular parameters, and its potential to overcome challenges in mapping vascular-related parameters. The review categorizes MRF-based imaging approaches, including MRF-arterial spin labeling (MRF-ASL), MR vascular fingerprinting (MRvF), and vascular fluid dynamics-MRF (VFD-MRF), highlighting their technical implementations, accuracy, and clinical applications in conditions such as stroke, brain tumors, and cerebrovascular diseases. We also explore the role of machine learning in enhancing dictionary matching and reducing computational time for more accurate and reliable real-time parameter estimation. The challenges such as low signal-to-noise ratios and computational demands are addressed through tailored sequence designs, noise-resilient dictionaries, and deep learning approaches. This comprehensive review provides a detailed technical framework for advancing the role of MRF in assessing cerebral physiology and its clinical translation.

Indexed as

BrainImage Processing, Computer-AssistedMagnetic Resonance ImagingAlgorithmsCerebrovascular CirculationHumansMachine LearningSignal-To-Noise RatioSpin LabelsSpin Labelscerebral physiologyneurovascular healthphysiological magnetic resonance fingerprintingquantitative MRIvascular hemodynamics

Identifiers

PMID41353764
PMCPMC12962212

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.