Evidence map›Paper›PMID 41355134›Full record

ReviewZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2025

[The logic of survival in patients with acute liver failure].

H L Weng

Abstract readReviewEnglish Abstract
In one paragraph

Review in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

H L WengDepartment of Medicine II, Section Molecular Hepatology, Faculty of Medicine Mannheim, Heidelberg University, Mannheim 68167, Germany.

Funding

German Research Foundation WE5009/9-1, WE5009/12-1
6 · The paper itself

Abstract

Massive hepatic necrosis (MHN) is defined as hepatocyte death exceeding 70% in the entire liver. Acute liver failure induced by MHN can lead to death in nearly half of patients. However, the vast majority of lost hepatocyte conditions can recover in about half of these patients. Hepatocyte function restoration and gradual differentiation into mature hepatocytes primarily rely on the rapid activation and proliferation of liver progenitor cells (LPCs) in these survived patients. This paper mainly describes the cellular and molecular mechanisms by which LPCs restore liver function and rescue patients following the occurrence of MHN.

Indexed as

HepatocytesLiverLiver Failure, AcuteMassive Hepatic NecrosisStem CellsCell ProliferationHumans

Identifiers

PMID41355134
PMCPMC12861779

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.