Evidence map›Paper›PMID 41355819›Full record

ArticleJournal of vascular surgery cases and innovative techniques2025

Persistent hypercoagulability and acute limb ischemia post COVID-19.

Natalia Penaloza, Emmanuel C Ebirim, Annie Cherner, Channa Blakely, Christine Shokrzadeh, Mitchell Cox

Abstract readCase Reports
In one paragraph

Article in Journal of vascular surgery cases and innovative techniques, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Natalia PenalozaJohn Sealy School of Medicine, University of Texas Medical Branch Galveston, Galveston, TX.
Emmanuel C EbirimJohn Sealy School of Medicine, University of Texas Medical Branch Galveston, Galveston, TX.
Annie ChernerDivision of Vascular and Endovascular Surgery, University of Texas Medical Branch Galveston, Galveston, TX.
Channa BlakelyDivision of Vascular and Endovascular Surgery, University of Texas Medical Branch Galveston, Galveston, TX.
Christine ShokrzadehDivision of Vascular and Endovascular Surgery, University of Texas Medical Branch Galveston, Galveston, TX.
Mitchell CoxDivision of Vascular and Endovascular Surgery, University of Texas Medical Branch Galveston, Galveston, TX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research indicates that COVID-19 induces endotheliitis, hypercoagulation, and hypofibrinolysis owing to virus-induced endothelial dysfunction. We present a case of a 34-year-old man with acute limb ischemia 4 days after COVID-19 diagnosis. Arterial duplex ultrasound examination revealed acute thrombosis of the popliteal artery and systemic anticoagulation was started. Despite multiple successful embolectomies and aggressive anticoagulant therapy, rethrombosis occurred, requiring bypass surgery approximately 1 year later. This case highlights the prolonged hypercoagulability post COVID-19 infection and the need for ongoing monitoring and tailored thromboprophylaxis to manage complications, especially with the evolving understanding of COVID-19-related hypercoagulability.

Indexed as

Case reportCOVID-19HypercoagulabilityThrombosis

Identifiers

PMID41355819
PMCPMC12675039

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.