ArticleInternational journal of general medicine2025
Hemoglobin Mass and Blood Volume at Moderate Altitude: Establishing Lean-Body-Mass-Adjusted Reference Values for Clinical Use.
Article in International journal of general medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Kinetics of Blood Volume and Hemoglobin Mass Adaptation in Sea-Level Newcomers Relocating to Moderate Altitude: A Six-Month Prospective Study.Journal of clinical medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Residing at high altitude is associated with increased red blood cell volume (RBCV) and reduced plasma volume (PV), changes that complicate interpretation of hemoglobin (Hb) and hematocrit (Hct). Here, we assess blood volume (BV), RBCV, PV, and hemoglobin mass (Hbmass) in individuals living at moderate altitude with the aim of deriving reference range for use in clinical practice. Methods: One hundred and fifty-eight moderate-altitude residents (ALT; 51 women) from Abha, Saudi Arabia (2250 m above sea level) were recruited and compared to 40 control subjects (CON; 0 women). Blood volumes and Hbmass were determined by carbon monoxide rebreathing. Lean body mass (LBM) was quantified by dual-energy X-ray absorptiometry and adjusted for. Results: When normalized to LBM, ALT men displayed an 8% increase in BV (109 vs 101 mL, Conclusion: Moderate altitude is associated with a higher BV owing to a higher RBCV, which also explains the elevated Hb. A reference range based on the 5% and 97.5% percentiles of blood volumes and Hbmass adjusted for LBM is suggested for use in clinical practice.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.