Evidence map›Paper›PMID 41355916›Full record

ArticleWorld journal of clinical oncology2025

Single-nucleotide variants in microRNAs associated with breast cancer in women from western Mexico.

Marcelo Victorio-De Los Santos, Andrés A Rodríguez-López, Jorge Gutiérrez-Franco, Amelia Rodríguez-Trejo, Zulia F Nieves-López, Rafael Torres-Valadez, Eloy A Zepeda-Carrillo, Marco F Flores-Reyes, Miriam F Ayón-Pérez, Alejandro Vázquez-Reyes

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Article in World journal of clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marcelo Victorio-De Los SantosLaboratorios de Investigación en Biología Molecular e Inmunología, Universidad Autónoma de Nayarit, Tepic 63000, Nayarit, Mexico.
Andrés A Rodríguez-LópezLaboratorios de Investigación en Biología Molecular e Inmunología, Universidad Autónoma de Nayarit, Tepic 63000, Nayarit, Mexico.
Jorge Gutiérrez-FrancoLaboratorios de Investigación en Biología Molecular e Inmunología, Universidad Autónoma de Nayarit, Tepic 63000, Nayarit, Mexico.
Amelia Rodríguez-TrejoCentro Estatal de Cancerología de Nayarit, Instituto Mexicano del Seguro Social-Bienestar, Tepic 63000, Nayarit, Mexico.
Zulia F Nieves-LópezCentro Nayarita de Innovación y Transferencia de Tecnología. Laboratorio de Investigación en Agrobiología, Universidad Autónoma de Nayarit, Tepic 63173, Nayarit, Mexico.
Rafael Torres-ValadezCentro Nayarita de Innovación y Transferencia de Tecnología, Unidad Especializada en Investigación, Desarrollo e Innovación en Medicina Genómica, Universidad Autónoma de Nayarit, Tepic 63173, Nayarit, Mexico.
Eloy A Zepeda-CarrilloCentro Nayarita de Innovación y Transferencia de Tecnología, Unidad Especializada en Investigación, Desarrollo e Innovación en Medicina Genómica, Universidad Autónoma de Nayarit, Tepic 63173, Nayarit, Mexico.
Marco F Flores-ReyesUnidad Académica de Medicina, Universidad Autónoma de Nayarit, Tepic 63000, Nayarit, Mexico.
Miriam F Ayón-PérezLaboratorios de Investigación en Biología Molecular e Inmunología, Universidad Autónoma de Nayarit, Tepic 63000, Nayarit, Mexico.
Alejandro Vázquez-ReyesLaboratorios de Investigación en Biología Molecular e Inmunología, Universidad Autónoma de Nayarit, Tepic 63000, Nayarit, Mexico. avazquez@uan.edu.mx.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicroRNAs play a key role in regulating gene expression in human cells. Single-nucleotide variants in these molecules have been linked to cancer development, particularly breast cancer (BrC).

aimTo analyze the association of three microRNA polymorphisms with the risk of BrC in women from western Mexico.

methodsThis case-control study included 71 women diagnosed with BrC and 215 women without BrC. Genotypes were determined using a real-time polymerase chain reaction allelic discrimination assay. Multiple genetic models - dominant, recessive, over-dominant, additive, and multiple comparison - were applied to assess the risk.

resultsThe over-dominant model showed that the C/T genotype of

conclusionThe C/T genotype of rs11614913 in

Indexed as

Breast cancerGenetic variantsMicroRNAsSingle-nucleotide variantWomen

Identifiers

PMID41355916
PMCPMC12678926

What Socratic holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.