Evidence map›Paper›PMID 41355955›Full record

ArticleTheranostics2026

Targeting NDUFS8 in basal forebrain ameliorates cognitive decline related to chronic cerebral hypoperfusion.

Yang Qu, Xiaoting Xu, Xuqiao Wang, Jinan Yang, Liye Zhang, Tao Wang, Xin Tang, Wei Cheng, Jing Li, Jing Ma and 11 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theranostics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Yang QuDepartment of Pharmacology, College of Pharmacy of Harbin Medical University, Harbin 150081, China.
Xiaoting XuDepartment of Pharmacology, College of Pharmacy of Harbin Medical University, Harbin 150081, China.
Xuqiao WangDepartment of Pharmacology, College of Pharmacy of Harbin Medical University, Harbin 150081, China.
Jinan YangDepartment of Pharmacology, College of Pharmacy of Harbin Medical University, Harbin 150081, China.
Liye ZhangDepartment of Pharmacology, College of Pharmacy of Harbin Medical University, Harbin 150081, China.
Tao WangInstitute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Department of Human Anatomy, Histology and Embryology, Neuroscience Center, Joint Laboratory of Anesthesia and Pain, School of Basic Medicine, Peking Union Medical College, Beijing 100006, China.
Xin TangDepartment of Pharmacology, College of Pharmacy of Harbin Medical University, Harbin 150081, China.
Wei ChengDepartment of Pharmacology, College of Pharmacy of Harbin Medical University, Harbin 150081, China.
Jing LiDepartment of Pathology and Electron Microscopic Center, Harbin Medical University, Harbin 150081, China.
Jing MaDepartment of Pharmacology, College of Pharmacy of Harbin Medical University, Harbin 150081, China.
Yan WuDepartment of Pharmacology, College of Pharmacy of Harbin Medical University, Harbin 150081, China.
Wentao XuDepartment of Pharmacology, College of Pharmacy of Harbin Medical University, Harbin 150081, China.
Qin WangDepartment of Pharmacology, College of Pharmacy of Harbin Medical University, Harbin 150081, China.
Lu ZengDepartment of Pharmacology, College of Pharmacy of Harbin Medical University, Harbin 150081, China.
Xiaobin AnDepartment of Pharmacology, College of Pharmacy of Harbin Medical University, Harbin 150081, China.
Dongyang WangDepartment of Pharmacology, College of Pharmacy of Harbin Medical University, Harbin 150081, China.
Meijie ChenDepartment of Pharmacology, College of Pharmacy of Harbin Medical University, Harbin 150081, China.
Guitian CongDepartment of Pharmacology, College of Pharmacy of Harbin Medical University, Harbin 150081, China.
Yonghui WuDepartment of Occupational Health, College of Public Health, Harbin Medical University, Harbin 150081, China.
Bin SunResearch Center for Pharmacoinformatic, College of Pharmacy of Harbin Medical University, Harbin 150081, China.
Jing AiDepartment of Pharmacology, College of Pharmacy of Harbin Medical University, Harbin 150081, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Basal ForebrainBrain IschemiaCognitive DysfunctionNADH DehydrogenaseAgedAnimalsCerebrovascular CirculationDisease Models, AnimalFemaleHumansMaleMitochondriaNF-E2-Related Factor 2Oxidative PhosphorylationRatsRats, Sprague-DawleyNADH DehydrogenaseNFE2L2 protein, humanNF-E2-Related Factor 2chronic cerebral hypoperfusioncognitive impairmentmitochondrial complex I deficiencyNDUFS8NRF2

Identifiers

PMID41355955
PMCPMC12679367

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.