ArticleAPL bioengineering2025
Mechanomedicine: Translating mechanical forces into therapeutic strategies.
Article in APL bioengineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- The Emerging Role of Mechanobiology in Connecting Metabolic and Cardiovascular Diseases: From Fundamentals to Future Therapies.Biomedicines · 2026Review
- Stress transmission towards the nucleus of the cell.Frontiers in cell and developmental biology · 2026Review
- Mechanomedicine in digestive surgery: a theranostic framework integrating mechanical diagnostics and therapeutic modulation across the perioperative continuum.Theranostics · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mechanomedicine is an emerging interdisciplinary field that applies the principles of mechanobiology to understand, diagnose, and treat disease. Recent advances reveal how mechanical cues such as stiffness, flow, and compression shape cell behavior, tissue function, and disease progression. Leveraging diverse tools, including organ-on-chip platforms, high-resolution force imaging, and synthetic mechanosensors, researchers have uncovered critical links between mechanotransduction and processes such as inflammation, aging, fibrosis, and tumor invasion. From reversible mechanomemory to programmable force-responsive circuits, these discoveries highlight the translational potential of targeting cellular mechanosensing for therapeutic innovation. Moving forward, integrating molecular biology, bioengineering, physics, and medicine will be essential to develop therapies that directly leverage the language of mechanical forces.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.