Evidence map›Paper›PMID 41356383›Full record

ReviewWorld journal of stem cells2025

Application of stem cell-derived exosomes in bone and joint diseases: Recent advances enabled by diverse carrier technologies.

Ya-Jun Fu, Jie Jian, Can Liu, Yang-Fei Yi, Yi-Tong Ding, Jie Wen, Yu-Fei Li, Qing-Jun Guo

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of stem cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ya-Jun FuDepartment of Anatomy, Hunan Normal University, Changsha 410013, Hunan Province, China.
Jie JianDepartment of Clinical Medicine, Hebei Medical University, Shijiazhuang 050017, Hebei Province, China.
Can LiuDepartment of Anatomy, Hunan Normal University, Changsha 410013, Hunan Province, China.
Yang-Fei YiDepartment of Anatomy, Hunan Normal University, Changsha 410013, Hunan Province, China.
Yi-Tong DingDepartment of Anatomy, Hunan Normal University, Changsha 410013, Hunan Province, China.
Jie WenDepartment of Pediatric Orthopedics, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha 410013, Hunan Province, China. cashwj@qq.com.
Yu-Fei LiDepartment of Anatomy, Hunan Normal University, Changsha 410013, Hunan Province, China.
Qing-Jun GuoDepartment of General Surgery and Operative Surgery, Hebei Medical University, Shijiazhuang 050017, Hebei Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone and joint diseases, such as osteoarthritis, exhibit significant pathological complexity. Current treatment modalities possess notable limitations, driving the development of cell-free regenerative treatment strategies centered on stem cell-derived exosomes, particularly mesenchymal stem cell-derived exosomes. Despite the promise of mesenchymal stem cell-derived exosomes, several challenges impede their clinical translation. These include rapid

Indexed as

Biomaterial scaffoldsBone and joint diseasesDelivery systemsOsteoarthritisStem cell-derived exosomes

Identifiers

PMID41356383
PMCPMC12679216

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.