ArticleCancer management and research2025
Correlation of 18F-FDG PET/CT SUV with Colon Cancer Aggressiveness and Superior Diagnostic Performance Over CT for Lymph Node Metastasis: A Retrospective Analysis.
Article in Cancer management and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To analyze the relationship between the standardized uptake value (SUV) derived from 18F-FDG PET/CT imaging and the clinical characteristics of colon cancer, and to evaluate its diagnostic performance relative to CT imaging in identifying lymph node metastasis. Methods: A retrospective analysis was conducted on 113 patients with pathologically confirmed primary colon cancer. All patients underwent preoperative 18F-FDG PET/CT and CT examinations. The SUV of the primary lesion was measured. Patients were grouped based on clinicopathological features, and differences in SUV across groups were analyzed. The diagnostic efficacy of PET/CT and CT for lymph node metastasis was evaluated using receiver operating characteristic (ROC) curves, with pathology as the gold standard. Results: The lesion SUV was not significantly related to sex, age, lesion location, CA199, or CA242 (P > 0.05). However, it was significantly associated with maximum lesion diameter (P < 0.001), AJCC stage (P = 0.001), pathological type (P < 0.001), differentiation grade (P < 0.001), lymph node metastasis (P < 0.001), and CEA expression (P < 0.001). Spearman correlation analysis showed that SUV was positively correlated with these significant parameters (all P < 0.05). For diagnosing lymph node metastasis, the area under the curve (AUC) for 18F-FDG PET/CT imaging was 0.943, which was significantly higher than that for CT imaging (0.836) (Z = 3.965, P < 0.05), with superior sensitivity and specificity. Conclusion: SUV values on 18F-FDG PET/CT are positively correlated with key indicators of tumor aggressiveness in colon cancer, including tumor size, stage, differentiation grade, and lymph node metastasis. 18F-FDG PET/CT demonstrates significantly better diagnostic performance than CT alone for the detection of lymph node metastasis.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.