Evidence map›Paper›PMID 41356605›Full record

ArticleJournal of aging research2025

Prevalence of Iron Deficiency Anaemia in Elderly Aged > 60 Taking Daily Low-Dose Aspirin.

Ali A Alaklabi, Abdulrahman S Altowaim, Hassan S Alqahtani, Abdulrahman A Bin Moammar, Abdulaziz T Alturki, Rakan A Al Muammar

Abstract read
In one paragraph

Article in Journal of aging research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ali A AlaklabiCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.ORCID https://orcid.org/0000-0002-9523-7240
Abdulrahman S AltowaimCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.ORCID https://orcid.org/0009-0004-6304-7794
Hassan S AlqahtaniCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.ORCID https://orcid.org/0009-0007-0299-8870
Abdulrahman A Bin MoammarCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.ORCID https://orcid.org/0009-0005-5687-9629
Abdulaziz T AlturkiCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.ORCID https://orcid.org/0009-0001-3161-086X
Rakan A Al MuammarCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.ORCID https://orcid.org/0009-0002-8145-1593

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron deficiency anaemia (IDA) and anaemia of chronic disease are both common causes of morbidity in the elderly population, where they increase hospitalization and mortality. The risk of IDA is increased in gastrointestinal bleeding caused by aspirin at low doses administered daily, which has been widely used to prevent cardiovascular diseases. The current research will compare the occurrence of IDA between patients under 81 mg of low-dose aspirin and nonaspirin users. The electronic medical records were reviewed for a retrospective cohort study in the King Abdulaziz Medical City, Riyadh, Saudi Arabia (2016-2023). The inclusion criteria were patients aged over 60 years who were taking 81 mg aspirin daily, and 1308 patients were included (654 aspirin users and 654 nonusers). The number of men using aspirin was 378 (56.5), and those not using it were 291 (43.5). The number of women using aspirin was 276 (43.2), and those not using it were 363 (56.8). In the IDA cases, there were 136 (20.8) and 165 (25.2) cases in aspirin and nonaspirin users, respectively. Although this was not a significant difference, the load of haemoglobin in aspirin users was markedly less with a high concentration of ferritin in the bloodstream than in nonusers. Hypertension was a risk factor for IDA. The IDA rates were higher in nonaspirin users in females, old patients and chronic steroid users. Aspirin and nonaspirin users did not differ significantly in terms of IDA incidence. Nonetheless, there were a decreased haemoglobin and an increased ferritin in aspirin users. Potential confounders may include age and BMI, which need to be considered when monitoring low-dose aspirin patients in old age.

Indexed as

elderly populationgastrointestinal bleedinghaemoglobin levelsiron deficiency anaemialow-dose aspirinretrospective cohort study

Identifiers

PMID41356605
PMCPMC12680471

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.