Evidence map›Paper›PMID 41356642›Full record

ArticleClinical case reports2025

Acellular Fish Skin for Deep Dermal Traumatic Wounds Management: A Case Report.

Esmaeil Biazar, Saeed Heidari-Keshel, Mahdiye Sadat Rezaee, Parisa Parsi, Hamideh Moravvej, Majid Rezaei Tavirani, Mostafa Rezaei Tavirani

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Esmaeil BiazarTissue Engineering Group, Department of Biomedical Engineering To.C., Islamic Azad University Tonekabon Iran.ORCID https://orcid.org/0000-0002-2367-2841
Saeed Heidari-KeshelHematopoietic Stem Cell Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0003-2637-2825
Mahdiye Sadat RezaeeProteomics Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.
Parisa ParsiProteomics Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.
Hamideh MoravvejSkin Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0002-9425-7282
Majid Rezaei TaviraniDepartment of Surgery, Faculty of Medicine Iran University of Medical Sciences Tehran Iran.
Mostafa Rezaei TaviraniProteomics Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.ORCID https://orcid.org/0000-0003-1767-7475

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wound dressings play a critical role in minimizing systemic inflammation and promoting scar-free healing. Among them, extracellular matrix (ECM)-based materials enriched with bioactive components show promise in accelerating tissue repair and regeneration. In this case report, deep dermal traumatic wounds of a 34-year-old woman were treated with a combination of platelet-rich fibrin gel (PRF), plasma-rich growth factor gel (PRGF), and acellular fish skin (AFS) grafts. Objective and subjective assessments were performed over a one-year follow-up period. The wounds treated with AFS demonstrated significantly faster healing, improved water retention, reduced pain, and superior functional and aesthetic outcomes compared to conventional treatments. Improvements included enhanced skin elasticity, thickness, and pigmentation. The synergistic application of PRF, PRGF, and decellularized fish skin grafts may serve as an effective alternative to split-thickness skin grafts for managing deep dermal wounds, offering accelerated healing and improved long-term outcomes.

Indexed as

acellular fish skinplatelet‐rich fibrintransplantationwound healingxenograft

Identifiers

PMID41356642
PMCPMC12680487

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.