Evidence mapPaperPMID 41356709Full record

SynthesisInternational journal of public health2025

Impact of Exercise Dose-Response on Maternal Mental Health and Perinatal Depression Prevention: A Systematic Review and Meta-Analysis.

Paulina Fuenzalida, Guillermo Droppelmann, Sandra Mahecha, Felipe Feijoo

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in International journal of public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Paulina FuenzalidaUniversidad Mayor Escuela de Medicina, Santiago, Chile.
Guillermo DroppelmannClínica MEDS, Santiago, Chile.
Sandra MahechaUniversidad Mayor Escuela de Medicina, Santiago, Chile.
Felipe FeijooSchool of Industrial Engineering, Pontificia Universidad Católica de Valparaíso, Valparaíso, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To estimate the effect of exercise on perinatal depressive symptoms, focusing on subclinical depression. Methods: Randomized controlled trials (RCTs) reporting Edinburgh Postnatal Depression Scale (EPDS) scores and evaluating perinatal exercise interventions were eligible. A systematic search was conducted in MEDLINE/PubMed, Web of Science, Scopus, and the Cochrane Library for studies published between 2000 and 2024. Study quality, risk of bias, and heterogeneity were assessed before synthesizing the results using a random-effects model. Results: Nine RCTs met the inclusion criteria. Exercise significantly reduced depressive symptoms (SMD = -0.47; 95% CI = -0.86 to -0.08; Conclusion: Exercise effectively reduces perinatal depressive symptoms and represents a valuable public health intervention. Longer follow-up periods (≥6 months) are needed to confirm the durability of benefits and to evaluate maternal and child outcomes. Future high-quality RCTs with standardized exercise protocols (≥150 min/week of moderate activity) will be essential to translate this evidence into actionable public health and clinical guidelines.

Indexed as

DepressionDepression, PostpartumExerciseMental HealthPregnancy ComplicationsFemaleHumansPregnancyRandomized Controlled Trials as Topicdepressionexerciseperinatal depressive symptomsphysical activitypregnancy

Identifiers

PMID41356709
PMCPMC12679042

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.