Evidence map›Paper›PMID 41356807›Full record

ReviewNature and science of sleep2025

The Complex Interplay Between Sleep and Healthy Aging: A Scoping Review.

Nicola Luigi Bragazzi, Carlotta Mutti, Pietro Luca Ratti, Alberto Sardella, Maria C Quattropani, Raffaele Lodi, Fabio Pizza, Francesco Biscarini, Dario Bottignole, Marco Salvi and 4 more

Abstract readReview
In one paragraph

Review in Nature and science of sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Nicola Luigi BragazziHuman Nutrition Unit (HNU), Department of Food and Drugs University of Parma, Parma, Italy.
Carlotta MuttiDepartment of Medicine and Surgery, Sleep Disorders Center, Parma University Hospital, Parma, Italy.
Pietro Luca RattiNeurocenter of Southern Switzerland, Regional Hospital of Lugano, Bellinzona, Switzerland.
Alberto SardellaDepartment of Educational Science, University of Catania, Catania, Italy.
Maria C QuattropaniDepartment of Educational Science, University of Catania, Catania, Italy.ORCID 0000-0003-0711-6412
Raffaele LodiDepartment of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
Fabio PizzaDepartment of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Francesco BiscariniDepartment of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Dario BottignoleDepartment of Medicine and Surgery, Sleep Disorders Center, Parma University Hospital, Parma, Italy.ORCID 0009-0003-1986-8096
Marco SalviMario Giovanni Terzano Interdepartmental Center for Sleep Medicine, University of Parma, Parma, Italy.ORCID 0000-0002-6798-2948
Marcello MaggioMario Giovanni Terzano Interdepartmental Center for Sleep Medicine, University of Parma, Parma, Italy.
Liborio ParrinoDepartment of Medicine and Surgery, Sleep Disorders Center, Parma University Hospital, Parma, Italy.
Giuseppe PlazziDepartment of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Christian FranceschiniDepartment of Medicine and Surgery, Sleep Disorders Center, Parma University Hospital, Parma, Italy.ORCID 0000-0002-9307-5209

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The relationship between sleep and healthy aging is complex, involving changes in sleep patterns, architecture, and disturbances. Recognizing these changes is crucial for maintaining physical, cognitive, social, and psychological well-being in older adults. However, links between sleep parameters and aging outcomes remain unclear. Objective: This review synthesizes current knowledge on associations between sleep parameters (duration, continuity, architecture, quality) and healthy aging outcomes, including physical health, cognitive function, psychological well-being, and social engagement. Methods: Following the Arksey and O'Malley framework and Joanna Briggs Institute guidelines, this scoping review analyzed observational studies on healthy older adults. Sleep-related measures were examined without confounders from mental or physical illnesses. Results: Twenty studies were included. Across cohorts, older adults consistently exhibited advanced sleep phases (bedtime ≈39 minutes earlier, wake time ≈76 minutes earlier) and reduced total sleep time (by approximately 2.4 hours vs younger adults). Both short and long sleep durations were associated with poorer aging outcomes, supporting a U-shaped relationship between sleep length and healthy aging. Sleep efficiency decreased by 13% and wake after sleep onset increased fourfold with age, particularly among women. Age-related reductions in slow-wave and REM sleep were linked to lower cognitive performance and altered mood regulation. Moderate daytime napping (<60 min/day) was generally associated with better sleep quality, whereas excessive napping correlated with reduced odds of "successful aging". Discrepancies between subjective and objective sleep assessments emerged, indicating that older adults may underreport sleep disturbances. Conclusion: Gaps in understanding longitudinal sleep data, the mechanisms of sleep's impact on aging, and napping's role need further exploration. Future research could inform interventions for promoting healthy aging.

Indexed as

healthy agingobjective sleepscoping reviewsleepsleep qualitysubjective sleep

Identifiers

PMID41356807
PMCPMC12676135

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.