Evidence map›Paper›PMID 41356838›Full record

ArticleFrontiers in nutrition2025

Non-sugar sweeteners and children: the current picture and controversies.

Maria João Campos, Liliana J G Silva, André M P T Pereira, Angelina Pena

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maria João Campos *LAQV, REQUIMTE, Laboratory of Bromatology and Pharmacognosy, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal.
Liliana J G Silva *LAQV, REQUIMTE, Laboratory of Bromatology and Pharmacognosy, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal.
André M P T Pereira *LAQV, REQUIMTE, Laboratory of Bromatology and Pharmacognosy, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal.
Angelina Pena *LAQV, REQUIMTE, Laboratory of Bromatology and Pharmacognosy, Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global effort to reduce childhood obesity and type 2 diabetes has increased the use of non-sugar sweeteners (NSS) as alternatives to sugar. However, the long-term health effects of NSS in children remain debated, with inconsistent evidence supporting a precautionary approach. This perspective article critically reviews current knowledge, highlights research gaps, and questions the broader context of NSS usage. There is a general consensus that the use of NSS is inadvisable before age 3 and strongly discouraged for those up to age 5. Beyond this age, uncertainties persist, especially regarding the benefits and risks for children who are overweight, obese, or have diabetes. There is an urgent need for robust, long-term studies on NSS exposure in children. Current regulatory measures such as varied labelling, school restrictions, and taxation reflect the lack of a unified scientific consensus and harmonised policies. To effectively protect children's health, it is essential to establish a global agreement and develop evidence-based guidelines on the use of NSS.

Indexed as

childrenhealth literacymarketing and labelsnon-communicable diseasesnon-nutritive sweetenerspolicies

Identifiers

PMID41356838
PMCPMC12678113

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.