Evidence map›Paper›PMID 41357271›Full record

ArticleHeart rhythm O22025

Significance of 3-dimensional cardiac anatomical axis as the predictor of low QRS amplitude of subcutaneous implantable cardioverter-defibrillator.

Yukihiro Uehara, Nobuhiko Ueda, Shumpei Mori, Takanori Kawabata, Kohei Ishibashi, Tsukasa Oshima, Toshihiro Nakamura, Satoshi Oka, Yuichiro Miyazaki, Akinori Wakamiya and 7 more

Abstract read
In one paragraph

Article in Heart rhythm O2, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Yukihiro UeharaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Nobuhiko UedaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Shumpei MoriDavid Geffen School of Medicine at University of California Los Angeles (UCLA), Los Angeles, California.
Takanori KawabataDepartment of Data Science, National Cerebral and Cardiovascular Center, Osaka, Japan.
Kohei IshibashiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Tsukasa OshimaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Toshihiro NakamuraDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Satoshi OkaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Yuichiro MiyazakiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Akinori WakamiyaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Kenzaburo NakajimaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Tsukasa KamakuraDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Mitsuru WadaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Yuko InoueDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Koji MiyamotoDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Takeshi AibaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.
Kengo KusanoDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: SMART Pass (SP) deactivation is associated with inappropriate shock from a subcutaneous implantable cardioverter-defibrillator (S-ICD). A low-amplitude subcutaneous electrogram (S-ECG) is a risk factor for SP deactivation; however, the cause of the low-amplitude of S-ECG is unclear. Objective: We aimed to investigate the relationship between the cardiac anatomical axis and S-ECG amplitude. Methods: We retrospectively investigated 73 patients who underwent S-ICD implantation between 2016 and 2021 using computed tomography data. The cardiac anatomical axis was defined as the line connecting the summit of the inferior pyramidal space, where the atrioventricular node is supposed to be located, and the apex of the left ventricle. We assessed the relationship between rightward, horizontal, and ventral rotations and the amplitude of the S-ECG in each vector. The primary en d point was SP deactivation. Results: There were significant correlations between rightward rotation and amplitude of the primary vector (R Conclusion: The cardiac anatomical axis and S-ECG amplitude are significantly correlated. Rightward rotation is a risk factor for SP deactivation.

Indexed as

Amplitude of subcutaneous electrogramCardiac anatomical axisInappropriate shocksSMART Pass deactivationSubcutaneous implantable cardioverter-defibrillator

Identifiers

PMID41357271
PMCPMC12675097

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.