ArticleJournal of diabetes research2025
Remnant Cholesterol Inflammatory Index and New-Onset Diabetes in Middle-Aged and Older Adults: Evidence From Prospective Surveys of Chinese and UK Populations.
Article in Journal of diabetes research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Association between remnant cholesterol inflammation index and erectile dysfunction among U.S. adults: a cross-sectional study.Translational andrology and urology · 2026Article
- Association between non-traditional lipid-inflammatory parameters and incident diabetes: a national prospective cohort study.BMC endocrine disorders · 2026Article
- The remnant cholesterol inflammatory index and risk of future cardiovascular disease in early CKM syndrome: findings from CHARLS.Journal of health, population, and nutrition · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: The aim of this study was to investigate the relationship between remnant cholesterol inflammatory index (RCII) and new-onset diabetes mellitus in middle-aged and elderly populations in China and United Kingdom. Methods: The total number of participants included in this study was 9946, comprising members of the Chinese Health and Retirement Longitudinal Study (CHARLS) cohort and the English Longitudinal Study of Ageing (ELSA) cohort. A comparison was made of the baseline characteristics of the two cohorts. Subsequently, a cox regression analysis was performed on the risk factors for diabetes. Subgroup analyses were conducted to explore the potential for effect modification across diverse subgroups. Results: The application of RCII quartile analyses revealed that the risk observed in the highest quartile (Q4) within the ELSA cohort was 8.49 times higher than that recorded in the lowest quartile (Q1). This finding was particularly significant for males. Similarly, the risk in the CHARLS cohort was 3.1 times higher than that in Q1. Following multi-model adjustment, the risk of diabetes exhibited a progressive increase from the second to the fourth quartile of RCII levels in both cohorts, with all associations demonstrating statistical significance. For each 1 kg/m Conclusions: Elevated RCII levels have been demonstrated to be significantly associated with an increased risk of future diabetes in middle-aged and older adults.
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