ArticleWorld journal of transplantation2025
Chronic kidney disease at one year after liver transplantation: Role of changes in immunosuppression over three decades.
Article in World journal of transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Rethinking chronic kidney disease risk after liver transplantation.World journal of transplantation · 2026Article
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundKidney disease is a common complication in liver transplant (LT) recipients, contributing to substantial morbidity and mortality. Calcineurin inhibitors are associated with short- and long-term decline in kidney function.
aimTo assess how changes in immunosuppression over three decades have impacted the evolution of renal function in the first year post-LT.
methodsThis single-center, observational, retrospective study was conducted in a tertiary hospital in Madrid. Adult patients who received a first LT in our center from 1987 to 2019 were included. Patients with simultaneous or prior transplantation of another organ and patients who required re-transplantation, or were lost to follow-up or died during the first year after transplantation were excluded. The development of chronic kidney disease (CKD) pre-transplant or at the first year after LT was analyzed.
resultsA total of 594 patients (median age: 52.9 years, 25
conclusionAge, female sex, pre-transplant RD, and CsA are associated with increased risk of CKD within 1 year after LT. Addition of MPA to Tac is associated with lower RD incidence.
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