ReviewNanoscale advances2026
Unveiling the potential of inorganic nanoparticle-based scaffolds in wound healing: advances in antimicrobial and regenerative strategies.
Review in Nanoscale advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Complex wound healing continues to be a significant clinical concern, demanding innovative interventions that actively promote tissue regeneration and infection control beyond the capabilities of standard dressings. Inorganic nanoparticle-based scaffolds have emerged as promising platforms, providing both localized antimicrobial action and regenerative support. The unique physicochemical properties of nanoparticles, including high surface area, controlled ion release, and redox activity, enable multiple mechanisms for the inhibition of biofilm formation and modulation of the wound microenvironment to stimulate immunomodulation, fibroblast migration, angiogenesis, and extracellular matrix deposition. This review critically evaluates scaffold fabrication strategies, including electrospun nanofibers, gas foaming, and 3D-printed constructs, and their influence on structural integrity, ion release kinetics, and biocompatibility. We further analyse the mechanisms underlying inorganic nanoparticle-mediated antimicrobial activity, emphasizing the interplay between direct surface interactions and sustained ionic release, and also provide a detailed assessment of various inorganic nanoparticle-based scaffolds as antimicrobial platforms. Despite considerable clinical progress, challenges remain in optimizing ion release, maintaining scaffold stability, and establishing standardized safety and efficacy evaluations. This review highlights the translational potential of inorganic nanoparticle-integrated scaffolds as multifunctional platforms for advanced wound care and underscores future directions for design optimization and clinical application.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.