Evidence mapPaperPMID 41357806Full record

SynthesisFrontiers in pediatrics2025

Transitioning care in cystic fibrosis: a comprehensive review of reviews of clinical and psychosocial outcomes.

Abdullah Alzayed

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Abdullah AlzayedDepartment of Pediatrics, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: With rising life expectancy in cystic fibrosis (CF), effective transition from pediatric to adult care is essential. Structured transition models are thought to improve continuity of care, clinical stability, and psychosocial outcomes. This review of reviews synthesizes systematic review evidence on the effectiveness of these models across healthcare systems. Methods: Reviews and systematic reviews with or without meta-analysis published between 2005 and 2025 were identified through comprehensive searches. Methodological quality was assessed using AMSTAR 2, and primary study overlap was quantified using the Corrected Covered Area (CCA). A narrative synthesis was conducted for all included reviews, stratified by intervention type and geography. Results: Structured programs consistently outperformed informal approaches. Joint pediatric-adult clinics were associated with preserved lung function and fewer hospitalizations. The use of readiness tools, such as the Transition Readiness Assessment Questionnaire, showed improvement in self-management skills. Transition coordinators enhanced adherence and improved patient satisfaction with care. Evidence was limited regarding the long-term impact on mortality or transplant status. Conclusion: Structured transition models, particularly those incorporating joint clinics and coordinator-led care, are effective in improving self-management, adherence, and continuity of care for adolescents and young adults with CF. Future systematic reviews should focus on synthesizing evidence for long-term clinical outcomes. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42025214760, PROSPERO CRD42025214760.

Indexed as

clinical outcomescystic fibrosispediatric to adult carepsychosocial outcomesreviewtransition programs

Identifiers

PMID41357806
PMCPMC12678278

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.