ArticleWorld journal of psychiatry2025
Psychological adjustment differences in ovarian cancer patients receiving different treatment modalities and their clinical significance.
Article in World journal of psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Reproductive concerns and quality of life among Chinese women undergoing fertility-sparing surgery for gynecologic malignancies: a mixed-methods study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
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4 authors.
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Abstract
backgroundOvarian cancer patients often face complex treatment processes and psychological challenges, with different treatment modalities potentially affecting patients' psychological adjustment abilities.
aimTo explore the differences in psychological adjustment patterns among ovarian cancer patients receiving surgery, chemotherapy, targeted therapy, and combined therapy, and to analyze their relationship with clinical outcomes.
methodsA retrospective analysis was conducted on the clinical data of 286 ovarian cancer patients who received different treatment modalities from January 2020 to December 2023. Patients were divided into surgery group (
resultsPatients in the combined therapy group had significantly higher Self-Rating Anxiety Scale (56.3 ± 7.2) and Self-Rating Depression Scale (58.4 ± 6.9) scores than other groups, with the highest incidence of anxiety (58.5%) and depression (62.2%); the targeted therapy group scored highest in the positive coping dimension (28.5 ± 3.6) and had the lowest incidence of anxiety and depression (29.5%/31.1%). Logistic regression analysis showed that positive coping (odds ratio = 2.86, 95% confidence interval: 1.75-4.68) and utilization of social support (odds ratio = 2.13, 95% confidence interval: 1.42-3.56) were protective factors for good treatment adherence. Longitudinal assessment showed that although all patients experienced increased anxiety and depression symptoms at 3 months of treatment, the targeted therapy group and surgery group showed significant improvement at 6 months (
conclusionDifferent treatment modalities significantly affect the psychological adjustment abilities of ovarian cancer patients, with combined therapy patients facing greater psychological challenges, while targeted therapy patients exhibit healthier psychological adjustment patterns.
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