Evidence map›Paper›PMID 41358014›Full record

ArticleNeurophotonics2025

Phantom for standardization in functional near-infrared spectroscopy, part 1: implementation and usage.

Hiroshi Kawaguchi, Yukari Tanikawa, Toru Yamada, Marianne Floor-Westerdijk, Miriam van der Hoek, Lin Yang, Alexander von Lühmann, Patrick Britz, David R Busch, Alessandro Torricelli and 3 more

Abstract read
In one paragraph

Article in Neurophotonics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hiroshi KawaguchiNational Institute of Advanced Industrial Science and Technology, Tsukuba, Japan.ORCID https://orcid.org/0000-0002-1496-2812
Yukari TanikawaNational Institute of Advanced Industrial Science and Technology, Tsukuba, Japan.
Toru YamadaNational Institute of Advanced Industrial Science and Technology, Tsukuba, Japan.ORCID https://orcid.org/0000-0002-1654-5166
Marianne Floor-WesterdijkArtinis Medical Systems, Elst, The Netherlands.
Miriam van der HoekArtinis Medical Systems, Elst, The Netherlands.
Lin YangNIRx Medizintechnik, Berlin, Germany.ORCID https://orcid.org/0000-0003-3266-6061
Alexander von LühmannNIRx Medizintechnik, Berlin, Germany.ORCID https://orcid.org/0000-0002-4995-293X
Patrick BritzNIRx Medizintechnik, Berlin, Germany.
David R BuschUniversity of Texas Southwestern Medical Center, Department of Anesthesiology & Pain Management, Biomedical Engineering, Neurology, Dallas, Texas, United States.ORCID https://orcid.org/0000-0002-9488-944X
Alessandro TorricelliPolitecnico di Milano, Dipartimento di Fisica, Milan, Italy.ORCID https://orcid.org/0000-0002-6878-8936
Antonio PifferiPolitecnico di Milano, Dipartimento di Fisica, Milan, Italy.ORCID https://orcid.org/0000-0002-2261-2089
Dirk GrosenickPhysikalisch-Technische Bundesanstalt, Berlin, Germany.
Heidrun WabnitzPhysikalisch-Technische Bundesanstalt, Berlin, Germany.ORCID https://orcid.org/0000-0002-3846-8659

Funding

Development of quantitative optical tools to continuously monitor cerebral autoregulation, blood flow, oxygenation and inflammation during pediatric extracorporeal life supportR01NS122119 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI David Richard Busch · 2022 to 2026
$3.2M
Development of a platform to non-invasively assess microvascular endothelial dysfunction at the bedside in COVID-19 patients throughout intensive care.R21EB031261 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI BUSCH, DAVID RICHARD · 2021 to 2021
$386k
NIBIB NIH HHS R21 EB031261NINDS NIH HHS R01 NS122119
6 · The paper itself

Abstract

Significance: The use of functional near-infrared spectroscopy (fNIRS) is expanding, including examples of devices approved for routine clinical use for specific indications. Instrument standardization is a critical element to facilitate clinical adoption. Currently, there is no published description of a phantom that meets the requirements of IEC 80601-2-71, the IEC/ISO standard for fNIRS equipment. Aim: We report an example of the implementation of the fNIRS standard phantom described in IEC 80601-2-71. We further report results from measurement campaigns with this phantom prototype in Japan and Europe. Approach: A phantom prototype was built and circulated among multiple academic and commercial fNIRS groups with diverse instrumentation. The phantom prototype was characterized by wavelength-dependent measurements of its diffuse optical features and utilized in a test for fNIRS signal magnitude as described in IEC 80601-2-71. Results: The optical loss of this phantom prototype as well as its change by varying an internal aperture were found to be Conclusions: The characteristics of the phantom prototype agreed with the specifications in the standard. The phantom prototype proved suitable for the related test in IEC 80601-2-71.

Indexed as

diffuse attenuationfunctional near infrared spectroscopyinternational standardperformance testsphantom

Identifiers

PMID41358014
PMCPMC12680081

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.