Evidence mapPaperPMID 41358472Full record

ArticleJournal of medicinal chemistry2025

Dual Agonist/Antagonist Modulation of α9-Containing Nicotinic Acetylcholine Receptors by 2-Ammoniumethyl Ethers of Stilbenol and Stilbenol Analogues.

Alessandro Giraudo, Han-Shen Tae, Andrew Hung, Katrin Richter, Bhavana Shivankar, Edoardo Armano, Veronika Grau, Marco Pallavicini, David J Adams, Cristiano Bolchi

Abstract read
In one paragraph

Article in Journal of medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alessandro GiraudoDepartment of Pharmaceutical Sciences, Università Degli Studi of Milan, Milano I-20133, Italy.ORCID 0000-0002-5291-0837
Han-Shen TaeMolecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW 2522, Australia.ORCID 0000-0001-8961-7194
Andrew HungSchool of Science, STEM College, RMIT University, Melbourne, Victoria 3001, Australia.
Katrin RichterDepartment of General and Thoracic Surgery, Laboratory of Experimental Surgery, Justus-Liebig-University, German Center for Lung Research [DZL], Cardio-Pulmonary Institute [CPI], Giessen 35385, Germany.
Bhavana ShivankarSchool of Science, STEM College, RMIT University, Melbourne, Victoria 3001, Australia.
Edoardo ArmanoDepartment of Pharmaceutical Sciences, Università Degli Studi of Milan, Milano I-20133, Italy.
Veronika GrauDepartment of General and Thoracic Surgery, Laboratory of Experimental Surgery, Justus-Liebig-University, German Center for Lung Research [DZL], Cardio-Pulmonary Institute [CPI], Giessen 35385, Germany.
Marco PallaviciniDepartment of Pharmaceutical Sciences, Università Degli Studi of Milan, Milano I-20133, Italy.ORCID 0000-0003-3344-484X
David J AdamsMolecular Horizons, Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, NSW 2522, Australia.ORCID 0000-0002-7030-2288
Cristiano BolchiDepartment of Pharmaceutical Sciences, Università Degli Studi of Milan, Milano I-20133, Italy.ORCID 0000-0002-6726-9501

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

2-(Cyclohexyldimethylammoniumethyl)ether of 4-stilbenol (

Indexed as

EthersNicotinic AgonistsNicotinic AntagonistsReceptors, NicotinicHumansMolecular Dynamics SimulationStructure-Activity RelationshipEthersNicotinic AgonistsNicotinic AntagonistsReceptors, Nicotinic

Identifiers

PMID41358472
PMCPMC12751000

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.