Evidence map›Paper›PMID 41359024›Full record

ArticleNucleic acids research2026

gutMSNP: a comprehensive database for human gut microbial single-nucleotide polymorphisms.

Kai Qian, Meiyu Du, Senwei Tan, Mingyang Ding, Meihui Song, Minke Lu, Changlu Qi, Liang Cheng, Xue Zhang

Abstract read
In one paragraph

Article in Nucleic acids research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kai QianCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang150081, China.
Meiyu DuCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang150081, China.
Senwei TanCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang150081, China.
Mingyang DingSchool of Basic Medical Sciences, Harbin Medical University, Harbin, Heilongjiang150081, China.
Meihui SongSchool of Basic Medical Sciences, Harbin Medical University, Harbin, Heilongjiang150081, China.
Minke LuSchool of Basic Medical Sciences, Harbin Medical University, Harbin, Heilongjiang150081, China.
Changlu QiCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang150081, China.
Liang ChengCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang150081, China.ORCID 0000-0002-6665-6710
Xue ZhangNational Health Commission (NHC) Key Laboratory of Molecular Probes and Targeted Diagnosis and Therapy, Harbin Medical University, Harbin150028, China.

Funding

National Natural Science Foundation of China 62172130National Natural Science Foundation of China 62222104
6 · The paper itself

Abstract

gutMSNP (https://bio-computing.hrbmu.edu.cn/gutMSNP/home) is a user-friendly database designed to provide a systematic and comprehensive resource for single-nucleotide polymorphisms (SNPs) in the human gut microbiome. Given that even a single SNP in gut microbial genomes can profoundly modulate microbial pathogenicity and thereby impact host health, a large-scale, standardized SNP repository is indispensable for elucidating microbial functions and the molecular mechanisms underpinning microbiota-driven disorders. The current release of gutMSNP includes: (i) 164 015 783 SNPs identified across human gut microbial genomes and categorized into three coverage confidence levels; (ii) 364 species-level and 8251 gene-level microbial records, each exhibiting phenotype-specific SNP distribution patterns; (iii) 8146 representative reference genomes of human gut microbes; and (iv) an online tool for capturing SNPs. The database enables users to search for SNPs in microbial species of interest along with detailed functional and positional annotations, explore phenotype-specific SNP distribution patterns in selected species and their associated genes, download reference genomes for downstream analyses, and detect as well as annotate SNPs in user-uploaded microbial genome files. With its massive SNP dataset, versatile query capabilities, and integrated analytical tools, gutMSNP will serve as a fundamental resource for SNP-based investigations in the human gut microbiome.

Indexed as

Databases, GeneticDatabases, Nucleic AcidGastrointestinal MicrobiomePolymorphism, Single NucleotideBacteriaGenome, BacterialHumansInternetSoftwareUser-Computer Interface

Identifiers

PMID41359024
PMCPMC12807719

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.