Evidence map›Paper›PMID 41359093›Full record

ArticleJournal of neuro-oncology2025

Accuracy of intra-operative brain tumor squash cytology compared to large excision biopsy: a comparative study at the University Teaching Hospital of Kigali (CHUK), Rwanda.

Delphine Uwamariya, Eric Niyodusenga, Jean Bosco Surwumwe, Angelique Umutesi, Bernard Ndayambaje, François Régis Muhire Musana, Marie Claire Ndayisaba, Gervais Ntakirutimana, Sylvie Inyange, Eric Shingiro and 6 more

Abstract readComparative Study
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Article in Journal of neuro-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Delphine UwamariyaDepartment of Pathology, University Teaching Hospital of Kigali, P.O. Box 655, Kigali, Rwanda. uwamariya94@gmail.com.
Eric NiyodusengaDepartment of Pathology, University Teaching Hospital of Kigali, P.O. Box 655, Kigali, Rwanda.
Jean Bosco SurwumweDepartment of Pathology, University Teaching Hospital of Kigali, P.O. Box 655, Kigali, Rwanda.
Angelique UmutesiDepartment of Pathology, University Teaching Hospital of Kigali, P.O. Box 655, Kigali, Rwanda.
Bernard NdayambajeDepartment of Pathology, University Teaching Hospital of Kigali, P.O. Box 655, Kigali, Rwanda.
François Régis Muhire MusanaDepartment of Pathology, University Teaching Hospital of Kigali, P.O. Box 655, Kigali, Rwanda.
Marie Claire NdayisabaDepartment of Pathology, University Teaching Hospital of Kigali, P.O. Box 655, Kigali, Rwanda.
Gervais NtakirutimanaDepartment of Pathology, University Teaching Hospital of Kigali, P.O. Box 655, Kigali, Rwanda.
Sylvie InyangeDepartment of Surgery, Neurosurgery Service, University Teaching Hospital of Kigali, P.O. Box 655, Kigali, Rwanda.
Eric ShingiroDepartment of Surgery, Neurosurgery Service, University Teaching Hospital of Kigali, P.O. Box 655, Kigali, Rwanda.
Steven NshutiDepartment of Surgery, Neurosurgery Service, University Teaching Hospital of Kigali, P.O. Box 655, Kigali, Rwanda.
Paulin MunyemanaDepartment of Surgery, Neurosurgery Service, University Teaching Hospital of Kigali, P.O. Box 655, Kigali, Rwanda.
Sévérien MunezaDepartment of Surgery, Neurosurgery Service, University Teaching Hospital of Kigali, P.O. Box 655, Kigali, Rwanda.
Augustin NzitakeraDepartment of Biomedical Laboratory Sciences, School of Health Sciences, College of Medicine and Health Sciences, University of Rwanda, P.O. Box 3286, Kigali, Rwanda.
Felix ManirakizaDepartment of Pathology, University Teaching Hospital of Kigali, P.O. Box 655, Kigali, Rwanda.
Belson RugwizangogaDepartment of Pathology, University Teaching Hospital of Kigali, P.O. Box 655, Kigali, Rwanda.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccurate brain tumor diagnosis guides effective management, with large excision biopsy as the gold standard. Intra-operative cytologic smear techniques offer rapid analysis, particularly useful in resource-limited settings. The aim of this study was to evaluate the diagnostic accuracy and clinical utility of intra-operative cytologic smear techniques in brain tumor surgery at the University Teaching Hospital of Kigali (CHUK).

objectivesTo evaluate the diagnostic accuracy and clinical utility of intra-operative cytologic smear compared to large excision biopsy in brain tumor surgery at CHUK.

methodsA prospective cross-sectional study involving 77 patients with radiologically confirmed brain tumors undergoing surgery at CHUK. Squash cytology diagnoses were compared with final histopathology diagnoses for concordance.

resultsSquash cytology showed 89.6% agreement with histopathology. Major tumor types such as gliomas and meningiomas were reliably identified, facilitating timely surgical decisions.

conclusionsIntra-operative squash cytology is a rapid and reliable adjunct to large biopsy, improving brain tumor management in low-resource settings. Integration of advanced techniques could enhance diagnostic precision further.

Indexed as

Brain NeoplasmsCytodiagnosisAdolescentAdultAgedBiopsyChildCross-Sectional StudiesFemaleHospitals, TeachingHospitals, UniversityHumansMaleMiddle AgedProspective StudiesRwandaAccuracyBrain tumorsDiagnosticsSquash Cytology

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.