ArticlePloS one2025
Co-infections of Schistosoma mansoni and Helicobacter pylori in school-aged populations and implication for management and control practices in Niger State, Nigeria.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Co-infection withParasite epidemiology and control · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Helicobacter pylori and Schistosoma mansoni are two important pathogens that infect the gastrointestinal tract, could be acquired earlier in childhood, and can remain asymptomatic for a long period. While S. mansoni is been controlled within routine primary healthcare program, there are no control guidelines for H. pylori. Here, we investigate the co-infection pattern of both pathogens to support improvement of management strategies. Fresh stool samples were obtained from 299 school-aged children between ages 6-17 years and analyzed using real-time and conventional polymerase chain reaction (PCR) for the direct detection of S. mansoni and H. pylori respectively. An overall prevalence of 19.7% (4.5% - 24.1%) was recorded for H. pylori, and 34.4% (0% - 42.1%) for S. mansoni, while co-infection of both was 7.0% (0% - 8.1%). Infections were significantly different across the study communities for S. mansoni (p = 0.00) when compared to H. pylori (p = 0.38). There were, however, no significant association between infection and gender (p > 0.05), with the following odds of infection for S. mansoni (OR=0.69, 95% CI: 0.42, 1.12), H. pylori (OR=1.33, 95% CI: 0.75, 2.36), and combination of both infections (OR=1.31, 95% CI: 0.83, 2.09). By age category, children below 14years were twice likely to be exposed to the combination of both infections; age 12-14 years (OR=1.9, 95% CI: 1.06, 3.44), and age 9-11 years (OR=1.96, 95% CI: 1.11, 3.48). But they were also less likely to be exposed to S. mansoni; age 12-14 years (OR=0.52, 95% CI: 0.27, 0.97), and age 9-11 years (OR=0.43, 95% CI: 0.23, 0.79). Our study highlights an unexpectedly high prevalence of S. mansoni, moderate prevalence of H. pylori, and very low coinfection prevalence for both. Our findings on S. mansoni are particularly concerning, suggesting potential challenges in control programs. It is therefore important to consider integrated interventions, including chemotherapy and improved water, sanitation, and hygiene (WASH) services.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.