Evidence map›Paper›PMID 41360736›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

METTL1-Mediated M

Manling Huang, Shuirong Lin, Yutong Zhao, Jiale Chen, Linyuan Huang, Yuyao Liu, Zixin Huang, Dongxin An, Yifan Zhang, Zimin Song and 9 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Manling HuangDepartment of Oncology, Cancer Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.
Shuirong LinCenter of Hepato-Pancreato-biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.
Yutong ZhaoDepartment of Oncology, Cancer Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.
Jiale ChenDepartment of Oncology, Cancer Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.
Linyuan HuangDepartment of Oncology, Cancer Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.
Yuyao LiuDepartment of Oncology, Cancer Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.
Zixin HuangDepartment of Ultrasound Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.
Dongxin AnDepartment of Urology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.
Yifan ZhangCenter of Hepato-Pancreato-biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.
Zimin SongCenter of Hepato-Pancreato-biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.
Xi YuCenter of Hepato-Pancreato-biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.
Yunpeng HuaCenter of Hepato-Pancreato-biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.
Jing WangCenter of Hepato-Pancreato-biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.
Weiwei WangCenter of Hepato-Pancreato-biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.
Yu GuoCenter of Hepato-Pancreato-biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.
Ming KuangCenter of Hepato-Pancreato-biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.
Fang WangDepartment of Oncology, Cancer Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.
Shuibin LinCenter for Translational Medicine, Institute of Precision Medicine, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.
Shunli ShenCenter of Hepato-Pancreato-biliary Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, 510080, P. R. China.ORCID https://orcid.org/0000-0002-3133-3508

Funding

Basic and Applied Basic Research Foundation of Guangdong Province 2022A1515010537Basic and Applied Basic Research Foundation of Guangdong Province 2023B1515230006National Key R&D Program of China 2022YFE0138700National Natural Science Foundation of China 82203083Natural Science Foundation and Science and Technology Project of Guangdong Province 2021A1515012321Natural Science Foundation and Science and Technology Project of Guangdong Province 2021B1515020075Natural Science Foundation and Science and Technology Project of Guangdong Province 2022A1515010071Natural Science Foundation of Guangdong Province 2022A1515010862
6 · The paper itself

Abstract

Partial hepatectomy (PHx) has emerged as a primary therapeutic intervention for end-stage liver pathologies. However, post-hepatectomy liver failure (PHLF), a critical complication arising from inadequate regenerative capacity of the remnant liver, underscores the clinical imperative to understand molecular mechanisms governing hepatic regeneration. Through an integrative multi-omics analysis in a murine 70% PHx model coupled with clinical correlation studies, the tRNA m

Indexed as

HepatectomyLiver RegenerationMethyltransferasesRNA, TransferAnimalsCell ProliferationHepatocytesHumansLiverMaleMiceMice, Inbred C57BLSignal TransductionMethyltransferasesMETTL1 protein, humanRNA, Transferhippo pathwayliver regenerationMETTL1post‐hepatectomy liver failure (PHLF)tRNA modification

Identifiers

PMID41360736
PMCPMC12948282

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.