Evidence mapPaperPMID 41361045Full record

ReviewJournal of general internal medicine2026

Preparing to Meet the Needs of a Growing Older Adult Population with Type 1 Diabetes: A Narrative Review.

Anna R Kahkoska, Joshua J Neumiller, Anastasia-Stefania Alexopoulos, Antoine Christiaens, Tali Cukierman-Yaffe, Nicole M Ehrhardt, Elbert S Huang, Thaer Idrees, Lori M Laffel, Sei J Lee and 9 more

Abstract readReview
In one paragraph

Review in Journal of general internal medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Anna R KahkoskaDivision of Endocrinology and Metabolism, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. anna_kahkoska@med.unc.edu.ORCID http://orcid.org/0000-0003-2701-101X
Joshua J NeumillerDepartment of Pharmacotherapy, College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, WA, USA.ORCID http://orcid.org/0000-0002-4734-7402
Anastasia-Stefania AlexopoulosDepartment of Medicine, Duke University School of Medicine, Durham, NC, USA.
Antoine ChristiaensClinical Pharmacy and Pharmoepidemiology Research Group, Louvain Drug Research Institute, Université Catholique de Louvain, Brussels, Belgium.
Tali Cukierman-YaffeDivision of Endocrinology, Metabolism and Diabetes, Sheba Medical Center, Ramat Gan, Israel.
Nicole M EhrhardtDepartment of Metabolism, Endocrinology and Nutrition, Medicine Diabetes Institute, University of Washington, Seattle, WA, USA.
Elbert S HuangDepartment of Medicine, University of Chicago, Chicago, IL, USA.
Thaer IdreesEmory University School of Medicine, Atlanta, GA, USA.
Lori M LaffelJoslin Diabetes Center, Boston, MA, USA.
Sei J LeeDivision of Geriatrics, School of Medicine, University of California, San Francisco, CA, USA.
Naushira PandyaDepartment of Geriatrics, Dr. Kiran C. Patel College of Osteopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL, USA.
Richard E PratleyAdvent Health Translational Research Institute, Orlando, FL, USA.
Leocadio Rodriguez-MañasServicio de Geriatria, Hospital Universitario de Getafe, Getafe, Spain.
Christine SlyneJoslin Diabetes Center, Boston, MA, USA.
Elena ToschiJoslin Diabetes Center, Boston, MA, USA.
Ruth S WeinstockDepartment of Medicine, Upstate Medical University, Syracuse, NY, USA.
Adriana WisniewskiDepartment of Anthropology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID http://orcid.org/0009-0002-8522-3870
Carol WyshamSection of Endocrinology and Metabolism, MultiCare Rockwood Clinic, Spokane, WA, USA.
Medha MunshiJoslin Diabetes Center, Boston, MA, USA.

Funding

Research Design, Data, and Analytics CoreP30DK092949 · UNIVERSITY OF CHICAGO · 2025 to 2025
$660k
From Biological to Social Processes: Interdisciplinary Training in Life Course ResearchT32HD091058 · UNIV OF NORTH CAROLINA CHAPEL HILL · 2025 to 2025
$538k
Building a Real-World Evidence Base for Continuous Glucose Monitoring in Older Adults with DiabetesK01AG084971 · UNIV OF NORTH CAROLINA CHAPEL HILL · 2025 to 2025
$127k
Foundation for the National Institutes of Health K01-AG084971Foundation for the National Institutes of Health K24AG069080Foundation for the National Institutes of Health OT2OD032581Foundation for the National Institutes of Health R01-AG060153Foundation for the National Institutes of Health R01-DK138060Foundation for the National Institutes of Health U01-DK127384-04Foundation for the National Institutes of Health U01-DK127392Foundation for the National Institutes of Health U01-DK35131Juvenile Diabetes Research Foundation United States of America SRA-2023-1416-S-BNational Science Foundation DGE-2439854NIA NIH HHS K01 AG084971NIA NIH HHS R01 AG063391NICHD NIH HHS T32 HD091058NIDDK NIH HHS P30 DK092949
6 · The paper itself

Abstract

The prevalence of diabetes is rising among older adults. While most diabetes cases in older adults are type 2 diabetes mellitus (T2D), advances in type 1 diabetes mellitus (T1D) management and rising rates of adult-onset T1D have translated into a growing number of individuals with T1D living into older adulthood. This narrative review integrates existing evidence on management of T1D in older adults with expert opinions to provide practical guidance for generalists increasingly encountering the unique challenges and complexities of this growing population. The profound heterogeneity in clinical presentation, pathobiology, and disease progression across the older adult population can make it challenging to differentiate older adults with T1D from those with insulin treated T2D, particularly in adult-onset cases. However, timely diagnosis is critical to minimize exposure to hyperglycemia and reduce the risk for complications, as individuals with T1D rely entirely on exogenous insulin and require intensive self-management to prevent acute complications like hypoglycemia and ketoacidosis. Self-management of T1D in older adults presents unique challenges, including a high risk of hypoglycemia that must be mitigated in the setting of a lifelong requirement for insulin and evolving mismatches between intensive self-management demands and an older person's capacity for self-care. The growing number of older adults with T1D underscores a lack of access to specialized care and limited training and resources for evidence-based management in primary care and post-acute/long-term care settings, as well as the dearth of high-quality clinical evidence specific to this population to inform care. Research to support changes across healthcare systems and at the policy level, in combination with education and multi-specialty collaboration, will ensure that healthcare providers and health systems are equipped and prepared to better meet the needs of the growing population of older adults with T1D.

Indexed as

Diabetes Mellitus, Type 1AgedHumansHypoglycemic AgentsInsulinSelf-ManagementHypoglycemic AgentsInsulinendocrinologygeriatricsinternal medicineolder adultstype 1 diabetes

Identifiers

PMID41361045
PMCPMC13004274

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.