Evidence map›Paper›PMID 41361070›Full record

ArticleNature immunology2026

DC subsets and states unraveled across human juxtatumoral and malignant tissues.

Kevin Mulder, Margaux Gardet, Wan Ting Kong, Amit Ashok Patel, Anne Calvez, Grégoire Gessain, Carlos de la Calle-Fabregat, Cécile Piot, Quentin Blampey, Elisa Poupaud and 21 more

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Nature immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

31 authors.

Kevin Mulder *INSERM U1015, Gustave Roussy, Paris-Saclay University, Villejuif, France.ORCID http://orcid.org/0000-0002-1568-6581
Margaux Gardet *INSERM U1015, Gustave Roussy, Paris-Saclay University, Villejuif, France.ORCID http://orcid.org/0009-0000-0226-7022
Wan Ting KongINSERM U1015, Gustave Roussy, Paris-Saclay University, Villejuif, France.
Amit Ashok PatelINSERM U1015, Gustave Roussy, Paris-Saclay University, Villejuif, France.
Anne CalvezCentre de Recherche des Cordeliers, INSERM, Sorbonne Université, USPC Université Paris Cité, Equipe Labellisée Ligue Nationale Contre le Cancer, Paris, France.ORCID http://orcid.org/0000-0003-3604-2125
Grégoire GessainINSERM U1015, Gustave Roussy, Paris-Saclay University, Villejuif, France.ORCID http://orcid.org/0000-0001-6800-0339
Carlos de la Calle-FabregatINSERM U1015, Gustave Roussy, Paris-Saclay University, Villejuif, France.ORCID http://orcid.org/0000-0002-3026-3069
Cécile PiotImmunobiology Laboratory, The Francis Crick Institute, London, UK.
Quentin BlampeyINSERM U981, PRISM Center, Gustave Roussy, Paris-Saclay University, Villejuif, France.
Elisa PoupaudINSERM U1015, Gustave Roussy, Paris-Saclay University, Villejuif, France.
Ahmed-Amine AnzaliINSERM U1015, Gustave Roussy, Paris-Saclay University, Villejuif, France.
Garett DunsmoreINSERM U1015, Gustave Roussy, Paris-Saclay University, Villejuif, France.
Antoine BougouinCentre de Recherche des Cordeliers, INSERM, Sorbonne Université, USPC Université Paris Cité, Equipe Labellisée Ligue Nationale Contre le Cancer, Paris, France.
Guilhem PupierCentre de Recherche des Cordeliers, INSERM, Sorbonne Université, USPC Université Paris Cité, Equipe Labellisée Ligue Nationale Contre le Cancer, Paris, France.ORCID http://orcid.org/0000-0001-6828-0465
Lizhi HeVizgen, Cambridge, MA, USA.
Timothy WigginsVizgen, Cambridge, MA, USA.
Jiang HeVizgen, Cambridge, MA, USA.
George EmanuelVizgen, Cambridge, MA, USA.
Anne-Gaëlle GoubetINSERM U1015, Gustave Roussy, Paris-Saclay University, Villejuif, France.
Ghamdan Al-EryaniBroad Institute of MIT and Harvard, Cambridge, MA, USA.
Alexander SwarbrickCancer Ecosystems Program, Garvan Institute of Medical Research, Darlinghurst, New South Wales, Australia.ORCID http://orcid.org/0000-0002-3051-5676
Judith MichelsINSERM U1186, Gustave Roussy, Paris-Saclay University, Villejuif, France.
Regine J DressInstitute of Systems Immunology, Hamburg Center for Translational Immunology (HCTI), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID http://orcid.org/0000-0001-8785-5471
Marc DelogerPlateforme de Bioinformatique, INSERM US23, CNRS UMS 3655, Université Paris-Saclay, Villejuif, France.ORCID http://orcid.org/0000-0002-6352-101X
Antonio BertolettiProgram in Emerging Infectious Disease, Duke-NUS Medical School, Singapore, Singapore.ORCID http://orcid.org/0000-0002-2942-0485
Vincent Thomas de MontprevillePathology Department, Marie Lannelongue Center, Le Plessis Robinson, France.ORCID http://orcid.org/0000-0001-7490-4000
Catherine Sautès-FridmanCentre de Recherche des Cordeliers, INSERM, Sorbonne Université, USPC Université Paris Cité, Equipe Labellisée Ligue Nationale Contre le Cancer, Paris, France.
Wolf H FridmanCentre de Recherche des Cordeliers, INSERM, Sorbonne Université, USPC Université Paris Cité, Equipe Labellisée Ligue Nationale Contre le Cancer, Paris, France.ORCID http://orcid.org/0000-0002-1332-0973
Laurence ZitvogelINSERM U1015, Gustave Roussy, Paris-Saclay University, Villejuif, France.ORCID http://orcid.org/0000-0003-1596-0998
Florent GinhouxINSERM U1015, Gustave Roussy, Paris-Saclay University, Villejuif, France. Florent_Ginhoux@a-star.edu.sg.ORCID http://orcid.org/0000-0002-2857-7755
Charles-Antoine DutertreINSERM U1015, Gustave Roussy, Paris-Saclay University, Villejuif, France. charles-antoine.dutertre@inserm.fr.ORCID http://orcid.org/0000-0001-7950-3652

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic cells (DCs) are professional antigen-presenting cells. While plasmacytoid DCs (pDCs) are poor antigen-presenting cells at steady state, myeloid DCs (mDCs), which include DC1s, DC2s and DC3s, are specialized in T cell priming. To generate unbiased human DC atlases, we integrated DCs from 13 tumor tissues across 40 datasets to create a pDC + mDC-VERSE (DC-VERSE) and an mDC-VERSE single-cell RNA-sequencing compendium. We characterized DC subsets and 'states' across these tissues. Most studied tumors contained CD207

Indexed as

Dendritic CellsNeoplasmsCD8-Positive T-LymphocytesHumansSingle-Cell AnalysisTumor Microenvironment

Identifiers

PMID41361070

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.