Evidence mapPaperPMID 41361124Full record

ReviewArchives of toxicology2026

Scorpion venom as a molecular treasure: emerging bioactive compounds and translational therapeutic insights.

Ritu Dahiya, Kanika Goyal, Kalicharan Sharma, Aruna Rawat, Vinita Sharma, Pooja Mathur

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of toxicology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ritu DahiyaSchool of Pharmacy, Lingaya's Vidyapeeth (Deemed to be University), Faridabad, Haryana, 121002, India. ritumalik1989@gmail.com.ORCID 0009-0006-3651-6342
Kanika GoyalGanpati Institute of Pharmacy, Yamuna Nagar, Bilaspur, Haryana, 135102, India.
Kalicharan SharmaISF College of Pharmacy, Ferozepur Road, NH 95, Ghal Kalan, Moga, Punjab, 142001, India.
Aruna RawatSchool of Pharmacy, Lingaya's Vidyapeeth (Deemed to be University), Faridabad, Haryana, 121002, India.
Vinita SharmaSchool of Medical and Allied Sciences, K R Mangalam University, Sohna Road, Gurugram, 121003, India.
Pooja MathurDepartment of Pharmacy, School of Healthcare and Allied Sciences, GD Goenka University, Sohna, Gurugram, Haryana, 121003, India. poojamathurkuk@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scorpion venom contains a diverse array of bioactive compounds, including peptides, proteins, enzymes, and alkaloids, which hold significant medicinal potential despite their toxicity due to interactions with voltage-gated sodium, potassium, and calcium channels affecting the autonomic nervous system. A comprehensive study analyzing literature from esteemed scientific databases (2000-2025) evaluates the structural and functional properties of these venom components. Enzymes and proteins exhibit anticancer properties through apoptosis induction, angiogenesis inhibition, and immune modulation, while ion channel modulators show promise in treating neurological disorders, pain, and cardiac arrhythmias. Antimicrobial peptides demonstrate high efficacy against multidrug-resistant (MDR) bacteria. Certain alkaloids also offer antioxidant and immunoregulatory benefits. A pioneering study on advanced nano-systems derived from scorpion venom has highlighted their potential to enhance drug delivery and therapeutic efficacy. Translational promise is further supported by advancements in recombinant expression, structure-activity relationship investigations, and innovative delivery strategies, despite challenges such as toxicity and stability. Scorpion venom thus represents a rich source of compounds with significant medicinal and biological applications.

Indexed as

Scorpion VenomsAnimalsHumansTranslational Research, BiomedicalScorpion VenomsComponents of scorpion venomEnvenomationVenomVenom peptides

Identifiers

PMID41361124

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.