Evidence map›Paper›PMID 41361515›Full record

SynthesisSurgical endoscopy2026

Treatment of Barrett's esophagus following sleeve gastrectomy by conversion to Roux-en-Y gastric bypass: a systematic review and pooled proportions analysis.

Thomas Armstrong, Abdullahi Mohamed, Brianna Brand, Sukhdeep Jatana, Janice Y Kung, Daniel J Meyer, Daniel W Birch, Noah J Switzer, Shahzeer Karmali

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Surgical endoscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Thomas Armstrong *Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Abdullahi Mohamed *Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Brianna BrandDepartment of Surgery, University of Alberta, Dvorkin Lounge Mailroom, 2G2 Walter C. Mackenzie Health Sciences Centre, 8440 - 112 ST NW Edmonton AB T6G 2B7, Alberta, Canada. babrand@ualberta.ca.ORCID 0009-0004-5737-0915
Sukhdeep JatanaDepartment of Surgery, University of Alberta, Dvorkin Lounge Mailroom, 2G2 Walter C. Mackenzie Health Sciences Centre, 8440 - 112 ST NW Edmonton AB T6G 2B7, Alberta, Canada.
Janice Y KungGeoffrey and Robyn Sperber Health Sciences Library, University of Alberta, Edmonton, AB, Canada.
Daniel J MeyerDepartment of Surgery, University of Calgary, Calgary, AB, Canada.
Daniel W BirchDepartment of Surgery, University of Alberta, Dvorkin Lounge Mailroom, 2G2 Walter C. Mackenzie Health Sciences Centre, 8440 - 112 ST NW Edmonton AB T6G 2B7, Alberta, Canada.
Noah J SwitzerDepartment of Surgery, University of Alberta, Dvorkin Lounge Mailroom, 2G2 Walter C. Mackenzie Health Sciences Centre, 8440 - 112 ST NW Edmonton AB T6G 2B7, Alberta, Canada.
Shahzeer KarmaliDepartment of Surgery, University of Alberta, Dvorkin Lounge Mailroom, 2G2 Walter C. Mackenzie Health Sciences Centre, 8440 - 112 ST NW Edmonton AB T6G 2B7, Alberta, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBarrett's esophagus (BE) is a metaplastic, premalignant condition that can develop following sleeve gastrectomy (SG). While various treatment modalities exist for management of post-SG BE, conversion to Roux-en-Y gastric bypass (RYGB) can be an effective option which can also improve gastroesophageal reflux disease (GERD). However, the effectiveness of RYGB for resolving BE has not been rigorously studied. This systematic review evaluates the outcomes of BE in patients converted from SG to RYGB.

methodsA comprehensive literature search was conducted in Ovid MEDLINE, Ovid Embase, PubMed, and Cochrane Library. Studies reporting BE onset following SG and subsequent RYGB conversion were included. Data extracted included patient demographics, Prague classification, dysplasia status, time from SG to BE diagnosis and time to RYGB conversion, and resolution of BE post-RYGB. The validated MINORS tool was used to assess the quality and risk of bias of reviewed studies.

resultsA total of 4 studies were included, comprising 21 patients who underwent conversion from SG to RYGB with BE. The weighted mean age at RYGB was 46.7 ± 13.8 years, with an initial BMI of 44.7 ± 2.7 kg/m

conclusionBased on these results, SG to RYGB conversion appears to be an effective intervention for BE, with the majority of patients achieving histological regression and resolution of symptoms. While preliminary findings indicate favorable outcomes, further studies with bigger sample sizes, longer follow-ups and more diverse patient pools are needed.

Indexed as

Barrett EsophagusGastrectomyGastric BypassObesity, MorbidPostoperative ComplicationsHumansTreatment OutcomeBariatric surgeryBarrett’s esophagusRoux-en-Y gastric bypassSleeve gastrectomySystematic review

Identifiers

PMID41361515

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.