Evidence map›Paper›PMID 41362659›Full record

ArticleDose-response : a publication of International Hormesis Society

The Value of Using 5T MRI T1ρ and T2 Mapping Sequences in Evaluating Muscle Changes Around Knee Osteoarthritis.

Min Fu, Zhaohui Yin, Jie Gan, Tianyu Bai, Hu Li, Zudong Yin, Lei Yu

Abstract read
In one paragraph

Article in Dose-response : a publication of International Hormesis Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Min FuDepartment of Radiology, Shandong Provincial Third Hospital, Shandong University, Jinan, China.
Zhaohui YinDepartment of Endocrinology, The 960th Hospital of PLA Joint Logistics Support Force, Jinan, China.
Jie GanDepartment of Radiology, Shandong Provincial Third Hospital, Shandong University, Jinan, China.
Tianyu BaiAcupuncture Department, Shandong Provincial Third Hospital, Shandong University, Jinan, China.
Hu LiAcupuncture Department, Shandong Provincial Third Hospital, Shandong University, Jinan, China.
Zudong YinDepartment of Radiology, Shandong Provincial Third Hospital, Shandong University, Jinan, China.
Lei YuDepartment of Radiology, Shandong Provincial Third Hospital, Shandong University, Jinan, China.ORCID https://orcid.org/0009-0001-2218-6374

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the value of 5T magnetic resonance imaging (MRI) T1ρ and T2 mapping sequences in evaluating muscle changes around knee osteoarthritis (KOA). Methods: 50 KOA patients and 36 healthy volunteers underwent knee MRI and peripheral muscle T1ρ/T2 mapping scans, comparing intergroup differences in each muscle's T1ρ/T2 values and analyzing their correlation with KOA severity. Results: The T1ρ and T2 values of the vastus medialis, vastus lateralis, biceps femoris, medial head of gastrocnemius, lateral head of gastrocnemius, and popliteus in KOA patients were higher than those in healthy volunteers, as well as the T2 values of the sartorius and semimembranosus. The T1ρ value of the vastus medialis is positively correlated with the whole-organ MRI score (WORMS) for the knee. The T2 values of the vastus medialis, sartorius, semimembranosus, popliteus, medial head of gastrocnemius, lateral head of gastrocnemius, biceps femoris and vastus lateralis are also positively correlated with the WORMS for the knee. Conclusion: The 5T MRI T1ρ and T2 mapping techniques can sensitively and quantitatively evaluate the changes in peri-articular muscles with KOA, providing important references for the clinical diagnosis and treatment of KOA.

Indexed as

5T MRIKOAmuscleT1ρT2 mapping

Identifiers

PMID41362659
PMCPMC12681677

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.