Evidence map›Paper›PMID 41362812›Full record

ArticleAnesthesiology research and practice2025

The Effect of Acupuncture on Pain, Prostaglandin E2, and Interleukin-6 in Septorhinoplasty Operations: A Randomized Clinical Trial.

Yavuz Orak, Filiz Alkan Baylan, Fatma Bilgen, Filiz Orak, Alper Ural, Sedat Yildiz, Saime Sagiroglu, Harun Karaduman, Adem Doganer

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Anesthesiology research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04009070 (Effect of Acupuncture on Nausea, Vomiting, Pain, PGE2 and IL 6 in Septorhinoplasty Operations; Prospective, Randomized, Controlled Study), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04009070 nacompletednot on this map

Effect of Acupuncture on Nausea, Vomiting, Pain, PGE2 and IL 6 in Septorhinoplasty Operations; Prospective, Randomized, Controlled Study

TypeinterventionalSponsorKahramanmaras Sutcu Imam UniversityRan2019 to 2020Enrolled70ConditionsPain, AcupunctureArmsAcupuncture Pres Needle: 0.22x1.5 mm needle
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yavuz OrakFaculty of Medicine, Department of Anesthesiology and Reanimation, Kahramanmaras Sutcu Imam University, Kahramanmaras, Türkiye, ksu.edu.tr.ORCID https://orcid.org/0000-0002-8356-6223
Filiz Alkan BaylanFaculty of Medicine, Department of Biochemistry, Kahramanmaras Sutcu Imam University, Kahramanmaras, Türkiye, ksu.edu.tr.ORCID https://orcid.org/0000-0003-3117-7768
Fatma BilgenDepartment of Plastic, Reconstructive and Aesthetic Surgery, Medilife Health Group, Istanbul, Türkiye.ORCID https://orcid.org/0000-0002-2127-3441
Filiz OrakFaculty of Medicine, Department of Microbiology, Kahramanmaras Sutcu Imam University, Kahramanmaras, Türkiye, ksu.edu.tr.ORCID https://orcid.org/0000-0001-5153-7391
Alper UralDepartment of Plastic, Reconstructive and Aesthetic Surgery, Memorial Ankara Hospital, Ankara, Türkiye, memorial.com.tr.ORCID https://orcid.org/0000-0001-8135-6444
Sedat YildizPhysical Medicine and Rehabilitation Department, Private Doctor's Office, Isparta, Türkiye.ORCID https://orcid.org/0000-0002-5531-8441
Saime SagirogluFaculty of Medicine, Department of Otorhinolaryngology, Kahramanmaras Sutcu Imam University, Kahramanmaras, Türkiye, ksu.edu.tr.ORCID https://orcid.org/0000-0003-2608-7274
Harun KaradumanFaculty of Medicine, Department of Plastic, Reconstructive and Aesthetic Surgery, Kahramanmaras Sutcu Imam University, Kahramanmaras, Türkiye, ksu.edu.tr.ORCID https://orcid.org/0000-0003-2696-7255
Adem DoganerFaculty of Medicine, Department of Biostatistics and Medical Informatics, Kahramanmaras Sutcu Imam University, Kahramanmaras, Türkiye, ksu.edu.tr.ORCID https://orcid.org/0000-0002-0270-9350

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The purpose of this study was to investigate the effects of acupuncture on pain, prostaglandin E2 (PGE2), and interleukin-6 (IL-6) levels during septorhinoplasty surgeries. Materials and Methods: This randomized, controlled study included 70 patients. The patients were divided into two groups: an acupuncture group ( Results: In terms of evaluating postoperative pain, no statistically significant differences were observed between the study groups with regard to VAS scores. At 30 min after surgery, fewer patients in the acupuncture group needed analgesics than in the control group ( Conclusions: The evidence from this study suggests that acupuncture can reduce the need for pain medication after septorhinoplasty surgery, and by decreasing IL-6 levels, it may contribute to the inflammatory process. Trial Registration: ClinicalTrials.gov: NCT04009070.

Identifiers

PMID41362812
PMCPMC12682433

What Socratic holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.