Evidence map›Paper›PMID 41363700›Full record

ReviewFEMS microbiology ecology2025

Ecology of the gut microbiota and colonization resistance: mechanisms and therapeutic implications.

Lanfan Liang, Ziyi Yang, Xiangsheng Fu

Abstract readReview
In one paragraph

Review in FEMS microbiology ecology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Evaluation ofMicroorganisms · 2026
    Article
  4. [Differential analysis of gut microbiome in patients with periprosthetic joint infection, aseptic failure, and osteoarthritis].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lanfan LiangDepartment of Gastroenterology, Clinical Medical College and the First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan 610500, P. R. China.
Ziyi YangDepartment of Gastroenterology, Clinical Medical College and the First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan 610500, P. R. China.
Xiangsheng FuDepartment of Gastroenterology, Clinical Medical College and the First Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan 610500, P. R. China.ORCID 0000-0001-8889-3314

Funding

Central Government-Directed Project for Local Science and Technology Development 2024ZYD0144Chengdu Medical College 2024kjTzn06Sichuan Provincial Health Commission 24WXXT05
6 · The paper itself

Abstract

The human gastrointestinal (GI) ecosystem is a highly dynamic environment and provides diverse microbial habitats for the gut microbiota, which are shaped by environmental factors, metabolic processes, and immune responses. The host-microbiota interactions in the gut form a balanced yet adaptable network. When invading microorganisms enter the GI tract, they deploy multiple strategies to overcome both host defences and competition from the resident microbiota. In turn, the host and native microbiota have evolved sophisticated mechanisms to prevent the colonization of invading organisms, collectively termed colonization resistance. Deciphering the mechanisms of interplay in the host‒microbe and microbe‒microbe relationships in the gut offers crucial insights into therapeutic interventions aimed at restoring or maintaining gut microbial homeostasis.

Indexed as

Gastrointestinal MicrobiomeGastrointestinal TractHost Microbial InteractionsAnimalsBacteriaHumanscolonization resistanceecologygut microbiotahosttherapeutic implications

Identifiers

PMID41363700
PMCPMC12728824

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.