Evidence map›Paper›PMID 41364285›Full record

ArticleMedical oncology (Northwood, London, England)2025

Ameliorative efficacy of Syzygium aromaticum ethanolic extract and Silymarin® upon carbon tetrachloride-induced liver fibrosis: antioxidant, antibacterial and anti-inflammatory activities.

Esmail M El-Fakharany, Mohamed H El-Sayed, Hend M Ali, Soad M Omar, Ashrakat M Sayed, Ahmed Atwa, Mohammad Y Alfaifi, Ali A Shati, Serag Eldin I Elbehairi, Zahrah R Alrayes and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Medical oncology (Northwood, London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Esmail M El-FakharanyProtein Research Department, Genetic Engineering and Biotechnology Research Institute (GEBRI), City of Scientific Research and Technological Applications (SRTA-City), New Borg Al-Arab City, Alexandria, 21934, Egypt. esmailelfakharany@yahoo.co.uk.
Mohamed H El-SayedDepartment of Biological Sciences, College of Science, Northern Border University, Arar, Saudi Arabia.
Hend M AliNutration and Food Science, Faculty of Specific Education, Assiut University, Assuit, Egypt.
Soad M OmarNutration and Food Science, Faculty of Specific Education, Assiut University, Assuit, Egypt.
Ashrakat M SayedNutration and Food Science, Faculty of Specific Education, Assiut University, Assuit, Egypt.
Ahmed AtwaZoology Department, Faculty of Science (Boys), Al-Azhar University, Cairo, 11884, Egypt.
Mohammad Y AlfaifiBiology Department, Faculty of Science, King Khalid University, 9004, Abha, Saudi Arabia.
Ali A ShatiBiology Department, Faculty of Science, King Khalid University, 9004, Abha, Saudi Arabia.
Serag Eldin I ElbehairiBiology Department, Faculty of Science, King Khalid University, 9004, Abha, Saudi Arabia.
Zahrah R AlrayesBiology Department, College of Science, Jouf University, Sakaka, Al-Jouf, Saudi Arabia.
Mervat Ahmed AbdRabouBiology Department, College of Science, Jouf University, Sakaka, Al-Jouf, Saudi Arabia.
Mahmoud AshryZoology Department, Faculty of Science, Al-Azhar University, Assuit, 71524, Egypt. mahmoud_ashry20@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver cirrhosis is associated with high morbidity and mortality rates and poses a serious threat to global health due to its rapid progression to cirrhosis and hepatocellular carcinoma. This study aims to assess the anti-fibrotic effect of combination of clove (Syzygium aromaticum) ethanolic extract (CEE) with Silymarin® on carbon tetrachloride (CCl

Indexed as

Anti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsLiver CirrhosisPlant ExtractsSilymarinSyzygiumAnimalsCarbon TetrachlorideEthanolHumansMaleRatsRats, WistarAnti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsCarbon TetrachlorideEthanolPlant ExtractsSilymarinCloveImmunomodulationLiver fibrosisOxidative stressSilymarin®Therapeutic

Identifiers

PMID41364285

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.