Evidence map›Paper›PMID 41364769›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

An electron transport complex required in the gut sensitizes

Hannah K Ratner, Brandon D Duong, Pengrui Miao, Savannah K Bertolli, Beth A Shen, Uma Mitchell, Larry A Gallagher, Matthew C Radey, S Brook Peterson, Joseph D Mougous

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hannah K RatnerDepartment of Microbiology, University of Washington, Seattle, WA 98109.
Brandon D DuongDepartment of Microbiology, University of Washington, Seattle, WA 98109.
Pengrui MiaoDepartment of Microbiology, University of Washington, Seattle, WA 98109.ORCID 0009-0006-3747-5271
Savannah K BertolliDepartment of Microbiology, University of Washington, Seattle, WA 98109.ORCID 0009-0006-4950-480X
Beth A ShenDepartment of Microbiology, University of Washington, Seattle, WA 98109.
Uma MitchellDepartment of Microbiology, University of Washington, Seattle, WA 98109.
Larry A GallagherDepartment of Microbiology, University of Washington, Seattle, WA 98109.ORCID 0000-0002-1517-4236
Matthew C RadeyDepartment of Microbiology, University of Washington, Seattle, WA 98109.
S Brook PetersonDepartment of Microbiology, University of Washington, Seattle, WA 98109.ORCID 0000-0003-2648-0965
Joseph D MougousDepartment of Microbiology, University of Washington, Seattle, WA 98109.ORCID 0000-0002-5417-4861

Funding

HHMI (HHMI) Investigator Award
6 · The paper itself

Abstract

Data suggest that antagonism between bacteria is prevalent within the gut microbiome. Such antagonism could have profound consequences on the fitness of species; however, the susceptibility determinants to even the most pervasive antagonistic factors in this ecosystem remain incompletely understood. Here, we screened for genetic factors that impact the susceptibility of

Indexed as

Bacterial ProteinsBacterial ToxinsBacteroidesGastrointestinal MicrobiomeType VI Secretion SystemsElectron TransportHumansBacterial ProteinsBacterial ToxinsType VI Secretion Systemsantagonismbacteroidesmetabolismmicrobiometoxin

Identifiers

PMID41364769
PMCPMC12718326

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.