ArticleNPJ science of food2025
Healthy dietary patterns for prevention of neuropsychiatric disorders: role of inflammatory and metabolic mechanisms.
Article in NPJ science of food, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Dietary Determinants of Mental Well-Being Among Cardiometabolic High-Risk Adults in Hungary.Nutrients · 2026Article
- Diet quality measured using the Mediterranean diet score and anxiety during armed conflict.Frontiers in nutrition · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Diet is increasingly being recognized as a modifiable lifestyle factor that plays an important role in neuropsychiatric health. However, existing research has focused on single foods or dietary patterns in relation to specific diseases, limiting their ability to inform precise dietary recommendations. Based on UK Biobank data, we applied Cox regression to assess associations between four healthy dietary patterns and risks of dementia, depression, and anxiety. Moreover, we utilized structural equation modeling to explore potential biological pathways. Our results indicated that Alternate Mediterranean Diet (AMED) demonstrated the strongest protective effect against all-cause dementia (0.92 (0.85-0.99)). Regarding depression, the AMED (0.93 (0.89-0.98)) and Alternative Healthy Eating Index-2010 (AHEI-2010) (0.93 (0.90-0.97)) showed the strongest negative correlation. AMED was also most strongly associated with reduced risk of phobic anxiety disorders (0.87 (0.77-0.99)), whereas AHEI-2010 exhibited the most pronounced inverse association with other anxiety disorders (0.94 (0.91-0.98)). Structural equation modeling indicated that healthy dietary patterns may reduce the risk of neuropsychiatric disorders partly through direct modulation of inflammation and partly by improving metabolic function, which in turn reduces inflammation. Collectively, our findings support the development of precision-targeted dietary recommendations for the diet-immune-brain axis.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.