Evidence map›Paper›PMID 41366067›Full record

ReviewCell biology and toxicology2025

Distinct mechanisms of cell in breast cancer and their clinical implication.

Aodi Li, Sishi Liu, Ying Xuan, Ying Liang, Lei Wang, Lei Zhao

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cell biology and toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aodi Li *Department of Medical Oncology, The First Hospital of China Medical University, Shenyang, Liaoning Province, China.
Sishi Liu *Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China.
Ying XuanDepartment of Oncology, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China.
Ying LiangDepartment of Hematology, The First Hospital of China Medical University, Shenyang, Liaoning Province, China. yliang@cmu.edu.cn.
Lei WangDepartment of Hematology, The First Hospital of China Medical University, Shenyang, Liaoning Province, China. leiwen000@sina.com.cn.
Lei ZhaoDepartment of Medical Oncology, The First Hospital of China Medical University, Shenyang, Liaoning Province, China. zhaolei@cmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is a heterogeneous disease affecting women globally. Despite significant advancements in therapeutic interventions in recent years, breast cancer remains a leading cause of cancer-related morbidity in women. Breast cancer's diverse molecular subtypes and escalating complexities in targeted therapies underscore the imperative need to explore novel therapeutic targets. The obstruction of apoptosis and the suppression of cell death are hallmarks of malignant tumors. Cell death, a pivotal regulatory event during tumorigenesis, includes apoptosis, anoikis, autophagy, necroptosis, ferroptosis, pyroptosis, and cuproptosis. This review systematically dissects the molecular underpinnings of cell death pathways in breast cancer, offering novel mechanistic insights and therapeutic opportunities to inform clinical management strategies.

Indexed as

Breast NeoplasmsAnimalsApoptosisAutophagyCell DeathFemaleFerroptosisHumansNecroptosisBreast cancerCell deathCuproptosisFerroptosisPyroptosis

Identifiers

PMID41366067
PMCPMC12790538

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.