ArticleBMC medical imaging2025
Comparison of reduced FOV diffusion-weighted imaging of rectal cancer at 5.0T ultra-high field versus 3.0T MRI: image quality and histopathological T staging.
Article in BMC medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
purposeTo compare image quality (IQ) of reduced field-of-view (rFOV) diffusion-weighted imaging (DWI) for rectal cancer at 5.0T compared with 3.0T and determine whether tumor apparent diffusion coefficient (ADC) values are correlated with histopathological T staging. MATERIALS AND
methodsIn a prospective cohort, 36 patients diagnosed with rectal cancer underwent MRI scans at both 3.0T and 5.0T systems. Two experienced radiologists independently evaluated the subjective and objective IQ parameters. Objective IQ metrics were statistically analyzed using paired t-test. Subjective assessments were compared using the Wilcoxon signed-rank test. Tumor ADC values obtained at the two magnetic field strengths were further compared, and their association with histopathological T staging was examined through Spearman's rank correlation.
resultsObjective measures demonstrated evidently improved IQ at 5.0T rFOV DWI relative to 3.0T (all P < 0.001). Subjective evaluations confirmed superior image clarity, lesion delineation, and overall diagnostic confidence at the 5.0T platform (P < 0.001). The two systems demonstrated comparable performance with respect to image artifacts and geometric distortions, showing no meaningful statistical divergence. However, the mean tumor ADC values differed significantly between 3.0T and 5.0T imaging (P < 0.001). A notable inverse correlation was identified between ADC values and histopathological T staging at both field strengths (P < 0.001).
conclusionrFOV DWI at 5.0T offers enhanced IQ and improved tumor visualization relative to 3.0T. The mean tumor ADC values were significantly different at 3.0T and 5.0T, which could be utilized for assessing histopathological T staging of rectal cancer.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.