Evidence map›Paper›PMID 41366505›Full record

ArticleAntimicrobial resistance and infection control2025

Incidence of central venous catheter-related bloodstream infections before, during, and after the SARS-CoV-2 pandemic: a registry-based cohort study.

Martin Schmidt-Hieber, Oliver Kriege, Jens Panse, Jan-Hendrik Naendrup, Boris Böll, Marcus Hentrich, Daniel Teschner, Enrico Schalk, SECRECY Investigators

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Antimicrobial resistance and infection control, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Martin Schmidt-HieberClinic of Haematology, Oncology, Pneumology, Nephrology and Diabetology, Medical University Lausitz - Carl Thiem (MUL-CT), Cottbus, Germany.ORCID 0000-0002-3071-6945
Oliver KriegeDepartment of Haematology and Medical Oncology, University Medical Centre of the Johannes Gutenberg University Mainz, Mainz, Germany.ORCID 0000-0002-3274-7390
Jens PanseDepartment of Oncology, Haematology, Haemostaseology and Stem Cell Transplantation, University Hospital RWTH Aachen, Aachen, Germany.ORCID 0000-0001-6316-3112
Jan-Hendrik NaendrupDepartment of Internal Medicine I, University Hospital of Cologne, Cologne, Germany.ORCID 0000-0002-6420-7938
Boris BöllDepartment of Internal Medicine I, University Hospital of Cologne, Cologne, Germany.ORCID 0000-0002-6432-0981
Marcus HentrichDepartment of Haematology and Oncology, Red Cross Hospital Munich, Munich, Germany.ORCID 0000-0001-5622-348X
Daniel TeschnerDepartment of Haematology and Medical Oncology, University Medical Centre of the Johannes Gutenberg University Mainz, Mainz, Germany.ORCID 0000-0001-7351-8060
Enrico SchalkDepartment of Haematology, Oncology and Cell Therapy, Medical Faculty, Otto von Guericke University Magdeburg, Leipziger Str. 44, 39120, Magdeburg, Germany. enrico.schalk@med.ovgu.de.ORCID 0000-0003-1892-5098
SECRECY Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhile the SARS-CoV-2 pandemic generally was associated with more healthcare-associated infections (HAI) we found fewer central venous catheter (CVC)-related bloodstream infections (CRBSI) during the pandemic as compared to the time period before in patients mainly with haematological malignancies. Since data on post-pandemic HAI are scarce, we conducted an analysis focused on post-pandemic CRBSI. We hypothesised that the CRBSI incidence has increased again after the SARS-CoV-2 pandemic.

methodsFor this cohort study, data were derived from a multicentre real-world registry on routine CVC surveillance in haematology and oncology departments in Germany. CRBSI ​​that occurred after and during the pandemic, respectively, were compared with those before the pandemic. Endpoints were CRBSI incidences and rates.

resultsA total of 1474, 1079, and 692 CVC from the pre-pandemic, pandemic, and post-pandemic period, respectively, were analysed. CVC were mostly used in patients with haematological malignancies. Compared to the CRBSI incidence of the pre-pandemic and pandemic cohorts (3.9 and 1.9/1000 CVC days, respectively; p < 0.001), the CRBSI incidence of the post-pandemic cohort was similar to the incidence of the pre-pandemic cohort (3.3/1000 CVC days; p = 0.43). Likewise, the CRBSI rate declined during the pandemic (6.0% vs. 2.9%; p < 0.001) and increased afterwards to a level comparable to that from the pre-pandemic period (4.8%; p = 0.29). In multivariable analysis, the time periods before and after the pandemic were independent CRBSI risk factors.

conclusionsOur data provide some evidence that following a temporary decline of CRBSI during the SARS-CoV-2 pandemic, CRBSI now returned to that observed in the pre-pandemic era.

Indexed as

Catheter-Related InfectionsCentral Venous CathetersCOVID-19Cross InfectionAdultAgedCatheterization, Central VenousCohort StudiesFemaleGermanyHematologic NeoplasmsHumansIncidenceMaleMiddle AgedPandemicsCentral venous catheterCentral venous catheter-related bloodstream infectionEpidemiologyHaematological malignanciesPandemicSARS-CoV-2

Identifiers

PMID41366505
PMCPMC12690893

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.