Evidence map›Paper›PMID 41366626›Full record

ArticleJapanese journal of radiology2026

Super-resolution deep learning reconstruction improves brain MRI quality and detection of metastases.

Yusuke Asari, Koichiro Yasaka, Jun Kanzawa, Yuki Sonoda, Takahiro Fukushima, Hiroaki Koyama, Saori Koshino, Shigeru Kiryu, Osamu Abe

Abstract read
In one paragraph

Article in Japanese journal of radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yusuke AsariDepartment of Radiology, Graduate School of Medicine, The University of Tokyo, 7- 3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Koichiro YasakaDepartment of Radiology, Graduate School of Medicine, The University of Tokyo, 7- 3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. koyasaka@gmail.com.ORCID http://orcid.org/0000-0002-0324-6562
Jun KanzawaDepartment of Radiology, Graduate School of Medicine, The University of Tokyo, 7- 3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Yuki SonodaDepartment of Radiology, Graduate School of Medicine, The University of Tokyo, 7- 3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Takahiro FukushimaDepartment of Radiology, Graduate School of Medicine, The University of Tokyo, 7- 3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Hiroaki KoyamaDepartment of Radiology, Graduate School of Medicine, The University of Tokyo, 7- 3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Saori KoshinoDepartment of Radiology, Graduate School of Medicine, The University of Tokyo, 7- 3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Shigeru KiryuDepartment of Radiology, International University of Health and Welfare Narita Hospital, 852 Hatakeda, Narita, Chiba, 286 - 0124, Japan.
Osamu AbeDepartment of Radiology, Graduate School of Medicine, The University of Tokyo, 7- 3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAccurate identification of brain metastases is critical for determining prognosis and guiding treatment. Deep learning reconstruction (DLR) enhances MRI quality by reducing noise, while super-resolution DLR (SR-DLR) may further improve spatial resolution and lesion detectability. To evaluate SR-DLR versus conventional DLR in detecting and visualizing brain metastases on postcontrast T1-weighted brain MRI. MATERIALS AND

methodsThis retrospective study included 47 consecutive patients who underwent postcontrast 3D whole-brain T1-weighted MRI between July and December 2024. Images were reconstructed using both SR-DLR and DLR. Three independent readers evaluated metastatic lesion detection and rated image quality. Subjective assessments included lesion visibility, visibility of normal structures, sharpness, noise, and overall image quality. Objective metrics-full width at half maximum (FWHM), edge rise distance (ERD), edge rise slope (ERS), signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR)-were also measured. Statistical tests included jackknife alternative free-response receiver operating characteristic (JAFROC) analysis, Wilcoxon signed-rank test, McNemar's test, and paired t-tests, with significance threshold of p < 0.050.

resultsA total of 117 brain metastases were detected in 47 patients (mean age, 59 years ± 18; 27 men). SR-DLR demonstrated significantly better lesion detection performance than DLR (mean figure of merit = 0.842 vs. 0.797; p = 0.042). Subjective image quality ratings favored SR-DLR for lesion and structure visibility, sharpness, noise, and overall quality in most cases. Objectively, SR-DLR yielded lower FWHM (1.2 mm vs. 1.9 mm; p < 0.001), higher ERS (791.3 mm

conclusionCompared to DLR, SR-DLR significantly enhances brain MRI quality and improves detection of metastatic lesions.

Indexed as

Brain NeoplasmsDeep LearningImage Interpretation, Computer-AssistedMagnetic Resonance ImagingAdultAgedAged, 80 and overBrainContrast MediaFemaleHumansMaleMiddle AgedRetrospective StudiesSignal-To-Noise RatioContrast MediaBrain metastasisDeep learningImage qualityMagnetic resonance imaging

Identifiers

PMID41366626
PMCPMC13038681

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.