ArticleInternational journal of retina and vitreous2025
Peeling of secondary epiretinal membrane in uveitis-functional improvement to be expected?
Article in International journal of retina and vitreous, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is a paucity of information regarding the results of patients with uveitis and secondary epiretinal membrane (sERM) who undergo pars plana vitrectomy and membrane peeling. This study aims to analyse the functional and anatomical outcomes and possible prognostic factors of a large cohort of eyes with uveitis-associated sERM who underwent vitrectomy with epiretinal membrane peeling.
methodsThe results of 76 eyes of 76 consecutive patients with uveitis-associated sERM who underwent pars plana vitrectomy with membrane peeling were analysed. The mean follow-up duration was 42.7 ± 47.9 months. Best-corrected visual acuity (BCVA) and central retinal thickness (CRT) before and after intervention were measured. Furthermore, demographic data, type of uveitis according to the Standardization of Uveitis Nomenclature (SUN) classification, benefit of additional peeling of the Membrana limitans interna (ILM), activity status of the uveitis at the time of surgery, lens status and postoperative complications were evaluated. Statistical tests included paired t tests, Wilcoxon signed-rank tests, Mann‒Whitney tests, and Kruskal‒Wallis H tests. Statistical significance was defined as p < 0.05; Holm‒Bonferroni correction was employed to address the cumulative risk of false-positive outcomes (type I error).
resultsCRT improved from 421.2 ± 133.2 µm prior to surgery to 331.7±142.5 µm at the final follow-up (p = 0.069), whereas BCVA deteriorated from a mean of 0.49 ± 0.30 logMAR to 0.56 ± 0.60 logMAR in the overall cohort (p > 0.99). The rate of concomitant cystoid macular edema decreased from 42.4% to 34.3%.
conclusionsThe indications for membrane peeling in patients with a secondary epiretinal membrane and uveitis should be considered carefully. Anatomical features can be positively influenced by pars plana vitrectomy with ERM peeling, whereas BCVA may only result in beneficial changes in carefully selected patients.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.