Evidence mapPaperPMID 41366735Full record

ArticleBMC plant biology2025

Green-synthesized silver nanoparticles from Camellia sinensis: mechanistic insights into phenolic-mediated multifunctional biological activities.

Adem Demir

Abstract read
In one paragraph

Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Adem DemirCentral Research Laboratory, Recep Tayyip Erdoğan University, Rize, 53100, Türkiye. adem.demir@erdogan.edu.tr.

Funding

Recep Tayyip Erdoğan University Development Foundation 02025010027751
6 · The paper itself

Abstract

backgroundGreen synthesis of silver nanoparticles (AgNPs) using plant extracts provides an eco-friendly route that bridges phytochemistry with nanobiotechnology. Camellia sinensis, rich in polyphenols, serves as an effective reducing and stabilizing agent in this process.Ethanolic extracts of C. sinensis leaves were characterized for phenolic composition by HPLC-DAD and utilized for AgNP synthesis (CS-AgNPs). The nanoparticles were characterized by UV-Vis, FTIR, XRD, SEM, EDX, and DLS. Biological properties were assessed through antioxidant (DPPH, ABTS), antibacterial (Gram-positive and Gram-negative strains), anti-inflammatory (BSA denaturation), and enzyme inhibitory (urease, α-glucosidase) assays, supported by molecular docking.

resultsEGCG was the dominant phenolic compound (54.8 ± 2.8 mg/g). CS-AgNPs displayed strong antioxidant (IC

conclusionsThis study highlights the dual role of C. sinensis phenolics in nanoparticle formation and bioactivity modulation, offering mechanistic insight into phenolic-metal interactions. Future work will focus on cytotoxicity and in vivo evaluations to validate the biomedical potential of CS-AgNPs.

Indexed as

Camellia sinensisMetal NanoparticlesPhenolsPlant ExtractsSilverAnti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsGreen Chemistry TechnologyMolecular Docking SimulationPlant LeavesAnti-Bacterial AgentsAnti-Inflammatory AgentsAntioxidantsPhenolsPlant ExtractsSilverAntibacterial activityAnti-inflammatoryCamellia sinensisEnzyme inhibitionHPLC-DADMolecular dockingSilver nanoparticles

Identifiers

PMID41366735
PMCPMC12743403

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.