Evidence map›Paper›PMID 41367362›Full record

ArticleChemPlusChem2026

Exploring RNA G-Quadruplex Stability in the Gas Phase: Insights from Native Mass Spectrometry.

Anna Ploner, Sarah Viola Heel, Kathrin Breuker

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ChemPlusChem, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Anna PlonerInstitute of Organic Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, Austria.ORCID 0009-0003-6816-4247
Sarah Viola HeelInstitute of Organic Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, Austria.
Kathrin BreukerInstitute of Organic Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, Austria.ORCID 0000-0002-4978-0883

Funding

Austrian Science Fund, and Österreichische Forschungsförderungsgesellschaft Grant FO999912210
6 · The paper itself

Abstract

Native mass spectrometry (MS) of ribonucleic acids (RNA) is a developing technique for the study of RNA structure and interactions that can provide important information on binding stoichiometry and binding motifs. However, the stabilities of key structural elements of RNA, including G-quadruplex structures, during and after desolvation are not well understood. Efforts to improve our understanding of RNA structures in the gas phase are complicated by the fact that the most common technique for transferring RNA from solution to the gas phase, electrospray ionization (ESI), typically produces ions with a relatively wide distribution of net charges. Here, we have studied two tetramolecular RNA G-quadruplexes with very different stabilities in solution by native MS. For both K

Indexed as

GasesG-QuadruplexesRNAPotassiumSpectrometry, Mass, Electrospray IonizationGasesPotassiumRNAcollisionally activated dissociationnative mass spectrometryquadruplexRNA

Identifiers

PMID41367362
PMCPMC12777508

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.