Evidence map›Paper›PMID 41367741›Full record

ArticleQuantitative imaging in medicine and surgery2025

The differentiation between primary aldosteronism and essential hypertension in left ventricular remodeling before and after treatment: a follow-up study with quantitative stress cardiac magnetic resonance imaging.

Leting Tang, Qian Long, Lu Yi, Kang Li, Feng Hou, Lin Tian, Hu Guo, Rongrong Cui, Mu Zeng

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Article in Quantitative imaging in medicine and surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Leting Tang *Department of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Qian Long *Department of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Lu YiDepartment of Urology, The Second Xiangya Hospital, Central South University, Changsha, China.
Kang LiDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Feng HouDepartment of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.
Lin TianCircle Cardiovascular Imaging Inc., Changsha, China.
Hu GuoMR Application, Siemens Healthineers Ltd., Changsha, China.
Rongrong Cui *National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital of Central South University, Changsha, China.
Mu Zeng *Department of Radiology, The Second Xiangya Hospital, Central South University, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Primary aldosteronism (PA) is associated with adverse cardiovascular outcomes. Elevated aldosterone levels in PA contribute to cardiac remodeling. This study aimed to apply cardiac magnetic resonance imaging (MRI) to longitudinally compare cardiac remodeling changes before and after targeted therapy between patients with PA and those with essential hypertension (EH) and to identify independent clinical predictors of left ventricular remodeling. Methods: We studied 75 consecutive patients with PA and 75 with EH. Patients with PA were treated with surgery, while patients with EH received pharmacotherapy. Clinical characteristics and MRI findings were collected at baseline and 6 months after treatment. Generalized estimating equations were applied to compare the changes in MRI variables. The relationship between the left ventricular remodeling parameters and physiological variables was analyzed via linear regression. Results: Median left ventricular mass {PA: 97 [interquartile range (IQR), 85-109] g; EH: 87 (IQR, 76-102) g; P=0.015} and mass index [PA: 54.40 (IQR, 47.22-65.22) g/m Conclusions: Patients with PA and those with EH demonstrated improvements in ventricular remodeling posttreatment, with the former exhibiting a more substantial degree of recovery. LogARR was an independent predictor of left ventricular remodeling.

Indexed as

essential hypertension (EH)magnetic resonance imaging (MRI)myocardial perfusionPrimary aldosteronism (PA)ventricular remodeling

Identifiers

PMID41367741
PMCPMC12682559

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.